DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10348 and AgaP_AGAP012686

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_307272.4	Gene:	AgaP_AGAP012686 / 1268706	VectorBaseID:	AGAP012686	Length:	240	Species:	Anopheles gambiae

Alignment Length:	190	Identity:	52/190 - (27%)
Similarity:	74/190 - (38%)	Gaps:	41/190 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   262 ELPHPNPKLSPVLPHPQLQDYQ-------------TRRKNKARTAATGGNATPNLPQRNKDRYTC 313
            ::..|..:.....|.|.:.||.             ...::::..||  ..:|...||| |.|..|
Mosquito     7 DVDEPEEESWETKPSPLVDDYPEGPAADDGYIYEVLETESESENAA--DCSTKPKPQR-KRRSFC 68

  Fly   314 KFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHNKERPFKCEICERCFG 378
            ..|||..   .||..|.|.|...:..:|.|||::|...:||..|: |||..:|.:|||.|...|.
Mosquito    69 TICGKYL---NNLAEHRRMHLNIRTQQCPYCEKTFVHRTNLITHL-NIHTHDRTYKCEYCGSEFT 129

  Fly   379 QQTNLDRHLKKHESDAVSLSA----------LSGVSERMH----------CIRRFCENPT 418
            ....|.:|...|.....:.:.          |....||:|          |.|:|. |||
Mosquito   130 SVQGLKQHRATHFEGQYACTICHRKYNRKCYLRIHHERVHRPKEKHCCLICDRQFL-NPT 188

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	25/62 (40%)
		zf-C2H2	311..333	CDD:278523	8/21 (38%)
		C2H2 Zn finger	313..333	CDD:275368	8/19 (42%)
		zf-H2C2_2	325..349	CDD:290200	9/23 (39%)
		C2H2 Zn finger	341..362	CDD:275368	9/20 (45%)
		zf-H2C2_2	353..377	CDD:290200	11/23 (48%)
		zf-C2H2	368..390	CDD:278523	7/21 (33%)
		C2H2 Zn finger	370..390	CDD:275368	6/19 (32%)
AgaP_AGAP012686	XP_307272.4	C2H2 Zn finger	68..85	CDD:275368	8/19 (42%)
		C2H2 Zn finger	93..113	CDD:275368	9/20 (45%)
		C2H2 Zn finger	121..141	CDD:275368	6/19 (32%)
		C2H2 Zn finger	148..169	CDD:275368	3/20 (15%)
		C2H2 Zn finger	177..197	CDD:275368	6/13 (46%)
		C2H2 Zn finger	205..224	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910