DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10348 and AgaP_AGAP012741

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_306506.3	Gene:	AgaP_AGAP012741 / 1267949	VectorBaseID:	AGAP012741	Length:	390	Species:	Anopheles gambiae

Alignment Length:	356	Identity:	76/356 - (21%)
Similarity:	128/356 - (35%)	Gaps:	94/356 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 PLDLRLAHKRKTDLVDQGPMEDENSNLIMFASE-----LAVAQQKEKELNNNHIAASLADLGFDM 152
            ||:|:.  ....|.|.:..:.||::::.:.|::     ::..:..|.|..|...:|:..:||...
Mosquito    74 PLELKF--DMLIDEVVETKLYDEDTSIQIIANQDARETVSCEEVAEAEEYNAPYSANYIELGEPF 136

  Fly   153 S---------RKMLRALREGGAGGGGGGGGGGGGGGGPPNAPPLTPPQCSIPAVHPTLLE----- 203
            |         ||.....|:....|                   ........|:..||:||
Mosquito   137 SDDTDTDEPKRKGKPRRRKADLNG-------------------TRSDATKQPSRTPTILENESDP 182

  Fly   204 AMTKNLPLQYRNVF---AGVLPGKVNSPAASSSPTGADFPFRH-PLK---KCELTWPPPTEQ--- 258
            ::....| :::.|.   .|:....::...||.:.. |:|...| |:|   ||.|.  ...:|
Mosquito   183 SLKPKAP-KHKKVLCYVCGIWITNIDGHIASHNKQ-ANFACPHCPVKMINKCNLM--RHVKQVHE 243

  Fly   259 ----LQLEL-----PHPNPKLSPVLPHPQLQDY-----------QTRRKNKARTAATGGNATPNL 303
                :..||     .|.|..:|.::.|...:.|           |...:|..|:.
Mosquito   244 KRIIMYCELCGKGFTHKNNYVSHMVSHNIGRTYDCSVCFVKFRHQGALRNHFRSV---------- 298

  Fly   304 PQRNKDRYTCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHNKERP- 367
              ...:.:.|..||.||.....|.||...|:.||||.|:.|.:.|.     .|:.|.||.....
Mosquito   299 --HLNETFPCATCGMVFRTPERLKRHQPVHSTEQPYVCRQCPKRFK-----YRYARTIHEITHTG 356

  Fly   368 --FKCEICERCFGQQTNLDRHLKKHESDAVS 396
              |:|..|::.:..:..|..|.:|...|:.|
Mosquito   357 VIFRCRHCDKSYRYKAQLKVHQRKTHPDSES 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	19/62 (31%)
		zf-C2H2	311..333	CDD:278523	8/21 (38%)
		C2H2 Zn finger	313..333	CDD:275368	8/19 (42%)
		zf-H2C2_2	325..349	CDD:290200	10/23 (43%)
		C2H2 Zn finger	341..362	CDD:275368	5/20 (25%)
		zf-H2C2_2	353..377	CDD:290200	7/26 (27%)
		zf-C2H2	368..390	CDD:278523	5/21 (24%)
		C2H2 Zn finger	370..390	CDD:275368	4/19 (21%)
AgaP_AGAP012741	XP_306506.3	zf-AD	<1..46	CDD:214871
		C2H2 Zn finger	196..213	CDD:275368	2/16 (13%)
		C2H2 Zn finger	221..242	CDD:275368	7/22 (32%)
		C2H2 Zn finger	250..270	CDD:275368	5/19 (26%)
		C2H2 Zn finger	306..326	CDD:275368	8/19 (42%)
		C2H2 Zn finger	334..354	CDD:275368	7/24 (29%)
		C2H2 Zn finger	361..382	CDD:275368	5/20 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910