Protein Alignment CG10348 and Klf4

DIOPT Version :10

• Sequence 1: NP_609904.2
• Gene: CG10348 / 35132
• FlyBaseID: FBgn0032707
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_446165.1
• Gene: Klf4 / 114505
• RGDID: 621445
• Length: 482
• Species: Rattus norvegicus
• Alignment Length: 503
• Identity: 119/503 - (23%)
• Similarity: 168/503 - (33%)
• Gaps: 173/503 - (34%)

  Fly    13 PSPKQGCVYPALGLIPTS----YISHV---------PYDLASSASVAATSSSSTSPTTTSATTTG 64
            |:.::..:.||..  ||:    .:||:         |||||  |:||....|..:....|:
  Rat    27 PAGREKTLRPAGA--PTNRWREELSHMKRLPPLPGRPYDLA--ATVATDLESGGAGAACSS---- 83

  Fly    65 RLQHQHSHQQHQTLNHHAKGKRRS-SFDQPLDLRLAHKRKTDLVDQGPMEDENSNLIMFASELAV 128
                          |:.|..:|.: .|:..|||        |.:....:..:.|......:..:.
  Rat    84 --------------NNPALPRRETEEFNDLLDL--------DFILSNSLSHQESVAATVTTSASA 126

  Fly   129 AQQKEKELNNNHIAASLADLGFDMSRKMLRALREGGAGGGGGGGGGGGGGGGPPNAPPLTPP--Q 191
            :.......:....|.|.....:        .:|.||..|...|..|||......:|||.|.|  .
  Rat   127 SSSSSPASSGPASAPSTCSFSY--------PIRAGGDPGVAAGNTGGGLLYSRESAPPPTAPFNL 183

  Fly   192 CSIPAVHPT---LLEAMTKNL-----PLQYRNVFAGVLPGK-------------VNSPAASS--- 232
            ..|..|.|:   :.|.:...|     |.|......|.|.||             ..||:..|
  Rat   184 ADINDVSPSGGFVAELLRPELDPVYIPPQQPQPPGGGLMGKFVLKASLSTPGSEYTSPSVISVSK 248

  Fly   233 -SPTGA----------------------------------------------------DFPFRHP 244
             ||.|:                                                    |||....
  Rat   249 GSPDGSHPVVVAPYSGGPPRMCPKIKQEAVPSCTVSRSLEAHLSAGPQLSNGHRPNTHDFPLGRQ 313

  Fly   245 LKKCELTWPPPTEQLQ-------LEL-----PHPNPKLSPVLPHPQLQD------YQTRRKNKAR 291
            |.........|.|.|.       |.|     |||.|...|.|| .|:|.      ||
  Rat   314 LPTRTTPTLSPEELLNSRDCHPGLPLPPGFHPHPGPSYPPFLP-DQMQSQVPSLHYQ-------- 369

  Fly   292 TAATGGNATPNLPQRNKDR----------YTCKF--CGKVFPRSANLTRHLRTHTGEQPYKCKY- 343
            .....|:..|..|:..:.|          :||.:  |||.:.:|::|..||||||||:||.|.:
  Rat   370 ELMPPGSCLPEEPKPKRGRRSWPRKRTATHTCDYAGCGKTYTKSSHLKAHLRTHTGEKPYHCDWD 434

  Fly   344 -CERSFSISSNLQRHVRNIHNKERPFKCEICERCFGQQTNLDRHLKKH 390
             |...|:.|..|.||.|. |...|||:|:.|:|.|.:..:|..|:|:|
  Rat   435 GCGWKFARSDELTRHYRK-HTGHRPFQCQKCDRAFSRSDHLALHMKRH 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_609904.2	zf-C2H2	311..333	CDD:395048	10/23 (43%)
		C2H2 Zn finger	313..333	CDD:275368	9/21 (43%)
		zf-H2C2_2	325..349	CDD:463886	13/25 (52%)
		C2H2 Zn finger	341..362	CDD:275368	8/22 (36%)
		zf-C2H2	368..390	CDD:395048	8/21 (38%)
		C2H2 Zn finger	370..390	CDD:275368	7/19 (37%)
Klf4	NP_446165.1	KLF4_N	7..399	CDD:409228	82/418 (20%)
		COG5048	<394..477	CDD:227381	34/83 (41%)
		C2H2 Zn finger	401..423	CDD:275368	9/21 (43%)
		C2H2 Zn finger	431..453	CDD:275368	8/22 (36%)
		zf-H2C2_2	445..470	CDD:463886	12/25 (48%)
		C2H2 Zn finger	461..481	CDD:275368	7/19 (37%)