DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10348 and Klf4

DIOPT Version :9

Sequence 1:NP_001286059.1 Gene:CG10348 / 35132 FlyBaseID:FBgn0032707 Length:540 Species:Drosophila melanogaster
Sequence 2:NP_446165.1 Gene:Klf4 / 114505 RGDID:621445 Length:482 Species:Rattus norvegicus


Alignment Length:503 Identity:119/503 - (23%)
Similarity:168/503 - (33%) Gaps:173/503 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly    13 PSPKQGCVYPALGLIPTS----YISHV---------PYDLASSASVAATSSSSTSPTTTSATTTG 64
            |:.::..:.||..  ||:    .:||:         |||||  |:||....|..:....|:    
  Rat    27 PAGREKTLRPAGA--PTNRWREELSHMKRLPPLPGRPYDLA--ATVATDLESGGAGAACSS---- 83

  Fly    65 RLQHQHSHQQHQTLNHHAKGKRRS-SFDQPLDLRLAHKRKTDLVDQGPMEDENSNLIMFASELAV 128
                          |:.|..:|.: .|:..|||        |.:....:..:.|......:..:.
  Rat    84 --------------NNPALPRRETEEFNDLLDL--------DFILSNSLSHQESVAATVTTSASA 126

  Fly   129 AQQKEKELNNNHIAASLADLGFDMSRKMLRALREGGAGGGGGGGGGGGGGGGPPNAPPLTPP--Q 191
            :.......:....|.|.....:        .:|.||..|...|..|||......:|||.|.|  .
  Rat   127 SSSSSPASSGPASAPSTCSFSY--------PIRAGGDPGVAAGNTGGGLLYSRESAPPPTAPFNL 183

  Fly   192 CSIPAVHPT---LLEAMTKNL-----PLQYRNVFAGVLPGK-------------VNSPAASS--- 232
            ..|..|.|:   :.|.:...|     |.|......|.|.||             ..||:..|   
  Rat   184 ADINDVSPSGGFVAELLRPELDPVYIPPQQPQPPGGGLMGKFVLKASLSTPGSEYTSPSVISVSK 248

  Fly   233 -SPTGA----------------------------------------------------DFPFRHP 244
             ||.|:                                                    |||....
  Rat   249 GSPDGSHPVVVAPYSGGPPRMCPKIKQEAVPSCTVSRSLEAHLSAGPQLSNGHRPNTHDFPLGRQ 313

  Fly   245 LKKCELTWPPPTEQLQ-------LEL-----PHPNPKLSPVLPHPQLQD------YQTRRKNKAR 291
            |.........|.|.|.       |.|     |||.|...|.|| .|:|.      ||        
  Rat   314 LPTRTTPTLSPEELLNSRDCHPGLPLPPGFHPHPGPSYPPFLP-DQMQSQVPSLHYQ-------- 369

  Fly   292 TAATGGNATPNLPQRNKDR----------YTCKF--CGKVFPRSANLTRHLRTHTGEQPYKCKY- 343
            .....|:..|..|:..:.|          :||.:  |||.:.:|::|..||||||||:||.|.: 
  Rat   370 ELMPPGSCLPEEPKPKRGRRSWPRKRTATHTCDYAGCGKTYTKSSHLKAHLRTHTGEKPYHCDWD 434

  Fly   344 -CERSFSISSNLQRHVRNIHNKERPFKCEICERCFGQQTNLDRHLKKH 390
             |...|:.|..|.||.|. |...|||:|:.|:|.|.:..:|..|:|:|
  Rat   435 GCGWKFARSDELTRHYRK-HTGHRPFQCQKCDRAFSRSDHLALHMKRH 481

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10348NP_001286059.1 COG5048 300..>363 CDD:227381 28/76 (37%)
zf-C2H2 311..333 CDD:278523 10/23 (43%)
C2H2 Zn finger 313..333 CDD:275368 9/21 (43%)
zf-H2C2_2 325..349 CDD:290200 13/25 (52%)
C2H2 Zn finger 341..362 CDD:275368 8/22 (36%)
zf-H2C2_2 353..377 CDD:290200 11/23 (48%)
zf-C2H2 368..390 CDD:278523 8/21 (38%)
C2H2 Zn finger 370..390 CDD:275368 7/19 (37%)
Klf4NP_446165.1 COG5048 <394..477 CDD:227381 34/83 (41%)
zf-C2H2 399..423 CDD:278523 10/23 (43%)
C2H2 Zn finger 401..423 CDD:275368 9/21 (43%)
C2H2 Zn finger 431..453 CDD:275368 8/22 (36%)
zf-H2C2_2 445..470 CDD:290200 12/25 (48%)
C2H2 Zn finger 461..481 CDD:275368 7/19 (37%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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