Protein Alignment CG10348 and ZNF234

DIOPT Version :9

• Sequence 1: NP_001286059.1
• Gene: CG10348 / 35132
• FlyBaseID: FBgn0032707
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_001138296.1
• Gene: ZNF234 / 10780
• HGNCID: 13027
• Length: 700
• Species: Homo sapiens
• Alignment Length: 213
• Identity: 61/213 - (28%)
• Similarity: 96/213 - (45%)
• Gaps: 46/213 - (21%)

  Fly   311 YTCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHNKERPFKCEICER 375
            |.|:.|||||.::::|..|.|.|:||:|:||:.|.:|||.|::||.| :.:|..|:|:||..|.:
Human   512 YNCEECGKVFSQASHLLTHQRVHSGEKPFKCEECGKSFSRSAHLQAH-QKVHTGEKPYKCGECGK 575

  Fly   376 CFGQQTNLDRHLK--------------KHESDAVSLSALSGVSERMHCIRRFCENPTEESYFEEI 426
            .|....|||.|.:              ||.|.|.||.....|            :..|:.|..::
Human   576 GFKWSLNLDMHQRVHTGEKPYTCGECGKHFSQASSLQLHQSV------------HTGEKPYKCDV 628

  Fly   427 RSFMGKVTQQQQQQQQQQQHDQQQQQHQSTATSASSSCSSSRDTPTSSHEEADHAPATSTADTAA 491
               .|||..:..|.|..::....::.::........|..|:    ..||.:. ||..|..
Human   629 ---CGKVFSRSSQLQYHRRVHTGEKPYKCEICGKRFSWRSN----LVSHHKI-HAAGTFY----- 680

  Fly   492 PSSSRDQEEEDSQPIMEL 509
                  :.:|:|:.|.||
Human   681 ------ENDENSKNIREL 692

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	24/51 (47%)
		zf-C2H2	311..333	CDD:278523	10/21 (48%)
		C2H2 Zn finger	313..333	CDD:275368	9/19 (47%)
		zf-H2C2_2	325..349	CDD:290200	11/23 (48%)
		C2H2 Zn finger	341..362	CDD:275368	9/20 (45%)
		zf-H2C2_2	353..377	CDD:290200	9/23 (39%)
		zf-C2H2	368..390	CDD:278523	8/35 (23%)
		C2H2 Zn finger	370..390	CDD:275368	7/33 (21%)
ZNF234	NP_001138296.1	KRAB	8..65	CDD:214630
		KRAB	8..47	CDD:279668
		KRNB	91..147
		COG5048	<101..306	CDD:227381
		C2H2 Zn finger	150..170	CDD:275368
		C2H2 Zn finger	178..198	CDD:275368
		zf-C2H2	204..226	CDD:278523
		C2H2 Zn finger	206..226	CDD:275368
		zf-H2C2_2	218..243	CDD:290200
		C2H2 Zn finger	234..254	CDD:275368
		COG5048	258..672	CDD:227381	53/179 (30%)
		C2H2 Zn finger	262..282	CDD:275368
		zf-H2C2_2	274..299	CDD:290200
		C2H2 Zn finger	290..310	CDD:275368
		C2H2 Zn finger	318..338	CDD:275368
		zf-H2C2_2	330..355	CDD:290200
		C2H2 Zn finger	346..366	CDD:275368
		zf-H2C2_2	359..383	CDD:290200
		C2H2 Zn finger	374..394	CDD:275368
		C2H2 Zn finger	402..422	CDD:275368
		zf-H2C2_2	414..439	CDD:290200
		C2H2 Zn finger	430..450	CDD:275368
		C2H2 Zn finger	458..478	CDD:275368
		zf-H2C2_2	471..495	CDD:290200
		C2H2 Zn finger	486..506	CDD:275368
		zf-H2C2_2	498..523	CDD:290200	7/10 (70%)
		C2H2 Zn finger	514..534	CDD:275368	9/19 (47%)
		zf-H2C2_2	526..551	CDD:290200	12/24 (50%)
		C2H2 Zn finger	542..562	CDD:275368	9/20 (45%)
		zf-H2C2_2	554..578	CDD:290200	9/24 (38%)
		C2H2 Zn finger	570..590	CDD:275368	7/19 (37%)
		zf-H2C2_2	582..607	CDD:290200	6/24 (25%)
		C2H2 Zn finger	598..618	CDD:275368	7/31 (23%)
		zf-H2C2_2	610..635	CDD:290200	8/39 (21%)
		C2H2 Zn finger	626..646	CDD:275368	5/22 (23%)
		zf-H2C2_2	639..662	CDD:290200	1/22 (5%)
		C2H2 Zn finger	654..674	CDD:275368	4/24 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910