DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10348 and znf977

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_021331166.1	Gene:	znf977 / 103910561	ZFINID:	ZDB-GENE-110913-138	Length:	765	Species:	Danio rerio

Alignment Length:	192	Identity:	60/192 - (31%)
Similarity:	92/192 - (47%)	Gaps:	27/192 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   307 NKDR-YTCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHNKERPFKC 370
            |::: :||..|||.|.:|:||.:|:|.||||:|:.|..|.:|||.||||..|:| ||..|:||.|
Zfish   425 NREKLFTCTQCGKNFNQSSNLNQHMRIHTGEKPFTCTQCGKSFSQSSNLNLHMR-IHTGEKPFTC 488

  Fly   371 EICERCFGQQTNLDRHLKKHESD----------AVSLSALSGVSERMHCIRRFCENPTEESYFEE 425
            ..|.:.|.|.::|:.|::.|..:          :.|.|::..:..|.|         |.|..|..
Zfish   489 SQCGKSFSQSSSLNLHMRIHTGEKPFTCTQCGKSFSQSSILNIHMRNH---------TGEKPFTC 544

  Fly   426 IRSFMGK-VTQQQQQQQQQQQHDQQQQQHQSTATSASSSCSSSRDTPTSSHEEADHAPATST 486
            ::  .|| .:|.....|..:.|   ..::..|.|....|.|:|.:............|.|.|
Zfish   545 LQ--CGKSFSQSTYLNQHMRIH---TGENLFTCTQCGKSFSNSANLNLHMRIHTGEKPFTCT 601

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	29/56 (52%)
		zf-C2H2	311..333	CDD:278523	11/21 (52%)
		C2H2 Zn finger	313..333	CDD:275368	10/19 (53%)
		zf-H2C2_2	325..349	CDD:290200	12/23 (52%)
		C2H2 Zn finger	341..362	CDD:275368	11/20 (55%)
		zf-H2C2_2	353..377	CDD:290200	11/23 (48%)
		zf-C2H2	368..390	CDD:278523	7/21 (33%)
		C2H2 Zn finger	370..390	CDD:275368	6/19 (32%)
znf977	XP_021331166.1	COG5048	8..415	CDD:227381
		C2H2 Zn finger	12..32	CDD:275368
		C2H2 Zn finger	40..60	CDD:275368
		C2H2 Zn finger	68..88	CDD:275368
		C2H2 Zn finger	96..116	CDD:275368
		C2H2 Zn finger	124..144	CDD:275368
		C2H2 Zn finger	152..172	CDD:275368
		C2H2 Zn finger	180..200	CDD:275368
		C2H2 Zn finger	208..228	CDD:275368
		C2H2 Zn finger	236..256	CDD:275368
		C2H2 Zn finger	264..284	CDD:275368
		C2H2 Zn finger	292..312	CDD:275368
		C2H2 Zn finger	320..340	CDD:275368
		COG5048	343..756	CDD:227381	60/192 (31%)
		C2H2 Zn finger	348..368	CDD:275368
		C2H2 Zn finger	376..396	CDD:275368
		C2H2 Zn finger	404..424	CDD:275368
		C2H2 Zn finger	432..452	CDD:275368	10/19 (53%)
		C2H2 Zn finger	460..480	CDD:275368	11/20 (55%)
		C2H2 Zn finger	488..508	CDD:275368	6/19 (32%)
		C2H2 Zn finger	516..536	CDD:275368	3/19 (16%)
		C2H2 Zn finger	544..564	CDD:275368	4/21 (19%)
		C2H2 Zn finger	572..592	CDD:275368	4/19 (21%)
		C2H2 Zn finger	600..620	CDD:275368	1/2 (50%)
		C2H2 Zn finger	628..648	CDD:275368
		C2H2 Zn finger	656..676	CDD:275368
		C2H2 Zn finger	684..704	CDD:275368
		C2H2 Zn finger	712..732	CDD:275368
		C2H2 Zn finger	740..760	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910