DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10348 and si:ch211-229l10.11

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_021331165.1	Gene:	si:ch211-229l10.11 / 103910550	ZFINID:	ZDB-GENE-110913-131	Length:	850	Species:	Danio rerio

Alignment Length:	255	Identity:	67/255 - (26%)
Similarity:	110/255 - (43%)	Gaps:	37/255 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   311 YTCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHNKERPFKCEICER 375
            :||..|||.|..||||.:|:|.||||:|:.|..|.:|||.|:||.:|:| ||..|:||.|..|.:
Zfish   206 FTCTQCGKSFSYSANLNQHMRIHTGEKPFTCTQCGKSFSNSANLNQHMR-IHTGEKPFTCTQCGK 269

  Fly   376 CFGQQTNLDRHLKKHESD----------AVSLSALSGVSERMH----------CIRRFCENPTEE 420
            .|.|.:.|::|::.|..:          :.|.|.......|:|          |.:.|.::   .
Zfish   270 SFSQSSYLNQHMRIHTGEKPFTCTQCGKSFSQSPYLNQHMRIHTGEKPFTCSQCGKSFSQS---S 331

  Fly   421 SYFEEIRSFMGK----VTQQQQQQQQQQQHDQQQQQHQSTATSASSSC--SSSRDTPTSSHEEAD 479
            |.:..:|...|:    .||..:...:....:...:.|..........|  |.|:.|..:.|....
Zfish   332 SLYLHMRIHTGEKPFTCTQCGKSFSKSSNLNIHMRNHTGEKPFTCLQCGKSFSQSTSLNLHMRIH 396

  Fly   480 HAPATSTADTAAPSSSRDQEEEDSQPIMELKRTLTSKLFPTTTADSAMTTPQTTSIKEEV 539
            ......|......|.|     :.|.|.:.::..:..|.|..|..:.:.:  |:||:..::
Zfish   397 TGEKPFTCTQCGKSFS-----QSSNPNIHMRNHIGEKPFTCTQCEKSFS--QSTSLNRQM 449

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	28/51 (55%)
		zf-C2H2	311..333	CDD:278523	12/21 (57%)
		C2H2 Zn finger	313..333	CDD:275368	11/19 (58%)
		zf-H2C2_2	325..349	CDD:290200	12/23 (52%)
		C2H2 Zn finger	341..362	CDD:275368	10/20 (50%)
		zf-H2C2_2	353..377	CDD:290200	11/23 (48%)
		zf-C2H2	368..390	CDD:278523	7/21 (33%)
		C2H2 Zn finger	370..390	CDD:275368	6/19 (32%)
si:ch211-229l10.11	XP_021331165.1	C2H2 Zn finger	12..32	CDD:275368
		zf-H2C2_2	25..49	CDD:316026
		C2H2 Zn finger	40..60	CDD:275368
		C2H2 Zn finger	68..88	CDD:275368
		zf-H2C2_2	80..105	CDD:316026
		SFP1	<90..169	CDD:227516
		C2H2 Zn finger	96..116	CDD:275368
		C2H2 Zn finger	124..144	CDD:275368
		C2H2 Zn finger	152..172	CDD:275368
		COG5048	176..580	CDD:227381	67/255 (26%)
		C2H2 Zn finger	180..200	CDD:275368
		C2H2 Zn finger	208..228	CDD:275368	11/19 (58%)
		C2H2 Zn finger	236..256	CDD:275368	10/20 (50%)
		C2H2 Zn finger	264..284	CDD:275368	6/19 (32%)
		C2H2 Zn finger	292..312	CDD:275368	3/19 (16%)
		C2H2 Zn finger	320..340	CDD:275368	4/22 (18%)
		C2H2 Zn finger	348..368	CDD:275368	2/19 (11%)
		C2H2 Zn finger	376..396	CDD:275368	5/19 (26%)
		COG5048	400..841	CDD:227381	11/57 (19%)
		C2H2 Zn finger	404..424	CDD:275368	4/24 (17%)
		C2H2 Zn finger	432..452	CDD:275368	4/20 (20%)
		C2H2 Zn finger	488..508	CDD:275368
		C2H2 Zn finger	517..537	CDD:275368
		C2H2 Zn finger	545..565	CDD:275368
		C2H2 Zn finger	573..593	CDD:275368
		C2H2 Zn finger	601..621	CDD:275368
		C2H2 Zn finger	629..649	CDD:275368
		C2H2 Zn finger	657..677	CDD:275368
		C2H2 Zn finger	685..705	CDD:275368
		C2H2 Zn finger	713..733	CDD:275368
		C2H2 Zn finger	741..761	CDD:275368
		C2H2 Zn finger	769..789	CDD:275368
		C2H2 Zn finger	797..817	CDD:275368
		C2H2 Zn finger	825..845	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910