DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10348 and si:ch73-221f6.1

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_009294177.1	Gene:	si:ch73-221f6.1 / 103909514	ZFINID:	ZDB-GENE-121214-41	Length:	510	Species:	Danio rerio

Alignment Length:	166	Identity:	53/166 - (31%)
Similarity:	76/166 - (45%)	Gaps:	16/166 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   310 RYTCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHNKERPFKCEICE 374
            |..|..|.|.|....||..|.|.||||:||||.:||.||:...:::.|:| ||.||||::|..|.
Zfish   280 RVQCDVCNKSFSTKGNLEAHKRIHTGERPYKCPHCEMSFNHKPHMKNHIR-IHTKERPYQCSECG 343

  Fly   375 RCFGQQTNLDRHLKKHESDAVSLSALSGVSERMHCIRRFCENPT----EESYFEEIRSFMGKVTQ 435
            :.||..|:|..|||.|..:.        ..:..||.:||.:...    |:::..|......:...
Zfish   344 KTFGNMTSLRSHLKIHSEEK--------PHQCKHCDKRFRQKSALTSHEKTHSGEKPYLCAECGM 400

  Fly   436 QQQQQQQQQQHDQQQQQHQSTATSASSSCSSSRDTP 471
            :...|.|...|   |:.|........:.|..|.:.|
Zfish   401 RFYIQAQMVYH---QRIHTGEKPYLCNICGRSFNKP 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	24/52 (46%)
		zf-C2H2	311..333	CDD:278523	8/21 (38%)
		C2H2 Zn finger	313..333	CDD:275368	8/19 (42%)
		zf-H2C2_2	325..349	CDD:290200	15/23 (65%)
		C2H2 Zn finger	341..362	CDD:275368	7/20 (35%)
		zf-H2C2_2	353..377	CDD:290200	10/23 (43%)
		zf-C2H2	368..390	CDD:278523	9/21 (43%)
		C2H2 Zn finger	370..390	CDD:275368	9/19 (47%)
si:ch73-221f6.1	XP_009294177.1	C2H2 Zn finger	199..219	CDD:275368
		C2H2 Zn finger	227..247	CDD:275368
		C2H2 Zn finger	255..275	CDD:275368
		COG5048	<260..495	CDD:227381	53/166 (32%)
		C2H2 Zn finger	283..303	CDD:275368	8/19 (42%)
		zf-H2C2_2	295..320	CDD:290200	16/24 (67%)
		C2H2 Zn finger	311..331	CDD:275368	7/20 (35%)
		zf-H2C2_2	323..346	CDD:290200	10/23 (43%)
		C2H2 Zn finger	339..359	CDD:275368	9/19 (47%)
		zf-H2C2_2	351..376	CDD:290200	9/32 (28%)
		C2H2 Zn finger	367..387	CDD:275368	5/19 (26%)
		C2H2 Zn finger	395..415	CDD:275368	4/22 (18%)
		zf-H2C2_2	411..431	CDD:290200	5/22 (23%)
		C2H2 Zn finger	423..443	CDD:275368	3/11 (27%)
		zf-H2C2_2	436..460	CDD:290200
		C2H2 Zn finger	451..471	CDD:275368
		zf-H2C2_2	464..488	CDD:290200
		C2H2 Zn finger	479..499	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910