DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10348 and si:dkey-40j3.3

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_021331332.1	Gene:	si:dkey-40j3.3 / 101884126	ZFINID:	ZDB-GENE-110913-109	Length:	1272	Species:	Danio rerio

Alignment Length:	213	Identity:	59/213 - (27%)
Similarity:	97/213 - (45%)	Gaps:	18/213 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   308 KDRYTCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHNKERPFKCEI 372
            |..:||.:|||.|.:|:|..:|:|.||||:|:.|.:|.:|||.|||..:|:| ||..|:||.|..
Zfish   707 KKPFTCTYCGKSFSQSSNFNKHMRIHTGEKPFTCTHCGKSFSQSSNFNKHMR-IHTGEKPFTCTY 770

  Fly   373 CERCFGQQTNLDRHLKKHESDAVSLSALSGVSERMHCIRRFCENPTEESYFEEIRSFMGK----V 433
            |.:.|.|.:|.::|::.|..:......        ||.:.|.::   .::.:.:|...|:    .
Zfish   771 CGKSFSQSSNFNKHMRIHTGEKPFTCT--------HCGKSFSQS---SNFNKHMRIHTGEKPFTC 824

  Fly   434 TQQQQQQQQQQQHDQQQQQHQSTATSASSSC--SSSRDTPTSSHEEADHAPATSTADTAAPSSSR 496
            :|..:...|....:|..:.|........:.|  |.|:.:..:.|..........|......|.||
Zfish   825 SQCGKSFSQSSNFNQHMKIHTGEKPFTCTHCGKSFSQSSNFNRHMSIHTGEKPFTCPQCGKSFSR 889

  Fly   497 DQEEEDSQPIMELKRTLT 514
            .......:.|...|:|.|
Zfish   890 SSTLSLHKKIHTGKKTFT 907

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	27/54 (50%)
		zf-C2H2	311..333	CDD:278523	10/21 (48%)
		C2H2 Zn finger	313..333	CDD:275368	9/19 (47%)
		zf-H2C2_2	325..349	CDD:290200	11/23 (48%)
		C2H2 Zn finger	341..362	CDD:275368	10/20 (50%)
		zf-H2C2_2	353..377	CDD:290200	10/23 (43%)
		zf-C2H2	368..390	CDD:278523	7/21 (33%)
		C2H2 Zn finger	370..390	CDD:275368	6/19 (32%)
si:dkey-40j3.3	XP_021331332.1	C2H2 Zn finger	12..32	CDD:275368
		COG5048	36..420	CDD:227381
		C2H2 Zn finger	40..60	CDD:275368
		C2H2 Zn finger	68..88	CDD:275368
		C2H2 Zn finger	96..116	CDD:275368
		C2H2 Zn finger	124..144	CDD:275368
		C2H2 Zn finger	152..172	CDD:275368
		C2H2 Zn finger	180..200	CDD:275368
		C2H2 Zn finger	208..228	CDD:275368
		C2H2 Zn finger	236..256	CDD:275368
		COG5048	260..667	CDD:227381
		C2H2 Zn finger	264..284	CDD:275368
		C2H2 Zn finger	292..312	CDD:275368
		C2H2 Zn finger	320..340	CDD:275368
		C2H2 Zn finger	348..368	CDD:275368
		C2H2 Zn finger	376..396	CDD:275368
		C2H2 Zn finger	404..424	CDD:275368
		C2H2 Zn finger	432..452	CDD:275368
		C2H2 Zn finger	460..480	CDD:275368
		C2H2 Zn finger	488..508	CDD:275368
		C2H2 Zn finger	516..536	CDD:275368
		C2H2 Zn finger	544..564	CDD:275368
		C2H2 Zn finger	572..592	CDD:275368
		C2H2 Zn finger	600..620	CDD:275368
		C2H2 Zn finger	628..648	CDD:275368
		C2H2 Zn finger	656..676	CDD:275368
		zf-H2C2_2	668..693	CDD:316026
		C2H2 Zn finger	684..704	CDD:275368
		COG5048	707..1149	CDD:227381	59/213 (28%)
		C2H2 Zn finger	712..732	CDD:275368	9/19 (47%)
		C2H2 Zn finger	740..760	CDD:275368	10/20 (50%)
		C2H2 Zn finger	768..788	CDD:275368	6/19 (32%)
		C2H2 Zn finger	796..816	CDD:275368	4/30 (13%)
		C2H2 Zn finger	824..844	CDD:275368	3/19 (16%)
		C2H2 Zn finger	852..872	CDD:275368	4/19 (21%)
		C2H2 Zn finger	880..900	CDD:275368	3/19 (16%)
		C2H2 Zn finger	908..928	CDD:275368	59/213 (28%)
		C2H2 Zn finger	936..956	CDD:275368
		C2H2 Zn finger	964..984	CDD:275368
		C2H2 Zn finger	992..1012	CDD:275368
		C2H2 Zn finger	1020..1040	CDD:275368
		C2H2 Zn finger	1048..1068	CDD:275368
		C2H2 Zn finger	1076..1096	CDD:275368
		C2H2 Zn finger	1104..1123	CDD:275368
		C2H2 Zn finger	1131..1151	CDD:275368
		zf-H2C2_2	1143..1168	CDD:316026
		C2H2 Zn finger	1159..1179	CDD:275368
		C2H2 Zn finger	1187..1207	CDD:275368
		C2H2 Zn finger	1215..1235	CDD:275368
		zf-H2C2_2	1227..1252	CDD:316026
		C2H2 Zn finger	1243..1263	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910