DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10348 and znf524

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_017950969.1	Gene:	znf524 / 101734696	-ID:	-	Length:	441	Species:	Xenopus tropicalis

Alignment Length:	337	Identity:	84/337 - (24%)
Similarity:	124/337 - (36%)	Gaps:	120/337 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   181 PPNAPPLTPPQCSI-------------PAVHPTL---------LEAMTKN--LP-LQY------R 214
            |...|.|.||...|             |||.|.|         :.:|.::  :| :.|      |
Frog   132 PFTTPLLKPPWSFIQNSSFPERDRMWNPAVKPHLHCEYPPMESVRSMEQDFLMPSVSYTSDAKDR 196

  Fly   215 NVFAGVLPGKVNSPAASSSPTGADFPFRHPLKKCELTWPPPTEQLQLELPHPNPKLSPV-----L 274
            .::...:...:|.|  |..|.     ...||..||      .|....   |.|....||     |
Frog   197 ELYQEKINSSINHP--SEDPA-----IGLPLALCE------PEDFSF---HSNSNCLPVNGTIDL 245

  Fly   275 PHPQLQD-----------------------YQTRRKNKARTAATGG--NATPNLPQR-------- 306
            ..|. ||                       |...:|:...:..|||  :....:|:|
Frog   246 TDPS-QDSKDESTCDSEENKFLLIDDRGIPYTVFKKDLINSPETGGELDEDSQIPKRFHYCPVCF 309

  Fly   307 -------NKDRYT----------CKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNL 354
                   :.:|::          ||.|||.|.||::|.||...||||:|::|..|::.|..|..|
Frog   310 RSFLYLSDLERHSITHSEHKPFECKVCGKSFKRSSHLQRHKHIHTGERPFQCIICKKGFRESGEL 374

  Fly   355 QRHVRNIHNKERPFKCEICERCFGQQTNLDRHLKK-------HESDAVSLSALSGVSERMHCIRR 412
            |||.| :|..|:|::||:|...|.::..|.||.|:       ::.|....|....|.|
Frog   375 QRHQR-VHTGEKPYQCELCHLRFTERNTLRRHTKRKHLKEMLYQQDPGDSSDWGEVIE------- 431

  Fly   413 FCENPTEESYFE 424
              :.|||::..|
Frog   432 --DIPTEDNNTE 441

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	28/87 (32%)
		zf-C2H2	311..333	CDD:278523	11/31 (35%)
		C2H2 Zn finger	313..333	CDD:275368	11/19 (58%)
		zf-H2C2_2	325..349	CDD:290200	10/23 (43%)
		C2H2 Zn finger	341..362	CDD:275368	9/20 (45%)
		zf-H2C2_2	353..377	CDD:290200	11/23 (48%)
		zf-C2H2	368..390	CDD:278523	8/28 (29%)
		C2H2 Zn finger	370..390	CDD:275368	8/26 (31%)
znf524	XP_017950969.1	SFP1	<248..411	CDD:227516	47/164 (29%)
		C2H2 Zn finger	305..325	CDD:275368	1/19 (5%)
		C2H2 Zn finger	333..353	CDD:275368	11/19 (58%)
		C2H2 Zn finger	361..381	CDD:275368	9/20 (45%)
		zf-H2C2_2	373..397	CDD:372612	11/24 (46%)
		C2H2 Zn finger	389..410	CDD:275368	8/20 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910