DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10348 and LOC100496074

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_002938649.3	Gene:	LOC100496074 / 100496074	-ID:	-	Length:	385	Species:	Xenopus tropicalis

Alignment Length:	344	Identity:	89/344 - (25%)
Similarity:	145/344 - (42%)	Gaps:	79/344 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   185 PPLTPPQ--CS----IPAVHPTLL-----EAMT---KNLPLQYRNVFAGVLPGKVNSPAASS--S 233
            |.||..:  |:    .|:.||.:|     :|.|   ..|.||.::.....: .:.|||.||:  .
Frog    74 PDLTKSKNCCNFTHGFPSHHPDILLRVKQQAQTLLSDQLELQEKSCRTSSV-DENNSPLASTHKE 137

  Fly   234 PTGA----------DF--------PFRHPLKKCELTWPPPTEQLQLELPHPNPKLSPVLPHPQLQ 280
            .||:          |:        .....:|:..|.|....|:.:   |...||..|
Frog   138 STGSSKLAGDRLAGDYLEDDNNEDQLPEKVKENILCWEDIFEKNE---PKSIPKEGP-------- 191

  Fly   281 DYQTRRKNKARTAATGGNATPNLPQRNKDR-YTCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYC 344
            :...|.:..|.|.....:..|::|   |:| |.|..|||.|..::.|.||:|.||||:|:.|.:|
Frog   192 NESERDEGLACTNPVKMDQKPSVP---KERLYICSVCGKSFGGNSLLVRHMRIHTGEKPFACNHC 253

  Fly   345 ERSFSISSNLQRHVRNIHNKERPFKCEICERCFGQQTNLDRHLKKHESDAVSLSALSGVSER--- 406
            ::||:..|.|.||:|. |..|:|:.|.:|.:||.|.:::..|::.|            ..||
Frog   254 DKSFNDKSYLLRHLRT-HTGEKPYSCSVCLKCFSQNSSVIAHMRIH------------TGERPFQ 305

  Fly   407 -MHCIRRFCENPTEESYF-EEIRSFMG----KVTQQQQQQQQQQQHDQQQQQHQSTATSASSSCS 465
             ..|.:||    :::||| ..:|:..|    |.:..::...|........:.|........|.|.
Frog   306 CPECEKRF----SDKSYFVRHMRTHSGEKPYKCSHCEKCFSQTSSLTSHMRIHTGEKPYKCSDCG 366

  Fly   466 S--SRDTPTSSHEEADHAP 482
            .  |:::..:.|:.. |.|
Frog   367 KCFSQNSSLALHKRL-HKP 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	28/63 (44%)
		zf-C2H2	311..333	CDD:278523	10/21 (48%)
		C2H2 Zn finger	313..333	CDD:275368	9/19 (47%)
		zf-H2C2_2	325..349	CDD:290200	12/23 (52%)
		C2H2 Zn finger	341..362	CDD:275368	9/20 (45%)
		zf-H2C2_2	353..377	CDD:290200	9/23 (39%)
		zf-C2H2	368..390	CDD:278523	6/21 (29%)
		C2H2 Zn finger	370..390	CDD:275368	6/19 (32%)
LOC100496074	XP_002938649.3	KRAB	10..66	CDD:214630
		COG5048	<203..373	CDD:227381	55/189 (29%)
		C2H2 Zn finger	222..242	CDD:275368	9/19 (47%)
		C2H2 Zn finger	250..270	CDD:275368	9/20 (45%)
		C2H2 Zn finger	278..298	CDD:275368	6/19 (32%)
		C2H2 Zn finger	306..326	CDD:275368	7/23 (30%)
		C2H2 Zn finger	334..354	CDD:275368	1/19 (5%)
		C2H2 Zn finger	362..382	CDD:275368	4/20 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910