DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10348 and LOC100495401

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_002931723.3	Gene:	LOC100495401 / 100495401	-ID:	-	Length:	1375	Species:	Xenopus tropicalis

Alignment Length:	296	Identity:	69/296 - (23%)
Similarity:	108/296 - (36%)	Gaps:	82/296 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   211 LQYRNVFAGVLPGKVNSPAASSSPTGADFPFRHPLKKCELTWPPPTEQLQLELPHPNPKL----- 270
            |..:|....:....:||....:..:.::....|...||...:...:..|..|..|...||
Frog  1103 LGMKNKTCRLCVNSINSTLTGNEDSTSNVRQTHTCSKCGKMFAQHSVFLLHERSHKEEKLHVCYA 1167

  Fly   271 --------SPVLPHPQL----QDYQ-------------------TRRKNKARTAATGG-----NA 299
                    ..:|.|.::    :.||                   :.::.|....|..|     ||
Frog  1168 CGKRFVQNQLLLRHEKIHKDRKPYQCMDCGRTFHGREMFVMHQRSHKEEKPFPCAECGKRFADNA 1232

  Fly   300 TPNLPQR---NKDRYTCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNI 361
            |..:..|   .:..:.|..|||.|.:.:.|..|.|.||||:||.|.||.|.||..|:...|||.
Frog  1233 TLTVHTRIHTGEKPFRCSACGKCFSQHSTLVSHQRIHTGEKPYSCHYCRRRFSDRSSYATHVRT- 1296

  Fly   362 HNKERPFKCEICERCFGQQTNLDRHLKKHESDAVSLSALSGVSERMH----------CIRRFCEN 416
            |..|:||.|..|.:.|.|.:||.||                  ||:|          |.:.|.:|
Frog  1297 HTGEKPFNCSGCGKSFSQSSNLRRH------------------ERIHTGQKPYACSVCGKTFNDN 1343

  Fly   417 PTEESYFEEIRSFMGKVTQQQQQQQQQQQHDQQQQQ 452
            ...:|:         :.|..:::...:..|.|:.::
Frog  1344 TKLKSH---------QKTHNKEETNVKLNHLQEAKR 1370

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	26/65 (40%)
		zf-C2H2	311..333	CDD:278523	8/21 (38%)
		C2H2 Zn finger	313..333	CDD:275368	8/19 (42%)
		zf-H2C2_2	325..349	CDD:290200	13/23 (57%)
		C2H2 Zn finger	341..362	CDD:275368	10/20 (50%)
		zf-H2C2_2	353..377	CDD:290200	9/23 (39%)
		zf-C2H2	368..390	CDD:278523	9/21 (43%)
		C2H2 Zn finger	370..390	CDD:275368	8/19 (42%)
LOC100495401	XP_002931723.3	KRAB	4..60	CDD:214630
		COG5048	950..1358	CDD:227381	67/282 (24%)
		C2H2 Zn finger	1137..1157	CDD:275368	4/19 (21%)
		C2H2 Zn finger	1165..1185	CDD:275368	2/19 (11%)
		C2H2 Zn finger	1193..1213	CDD:275368	0/19 (0%)
		C2H2 Zn finger	1221..1241	CDD:275368	6/19 (32%)
		C2H2 Zn finger	1249..1269	CDD:275368	8/19 (42%)
		C2H2 Zn finger	1277..1297	CDD:275368	10/20 (50%)
		C2H2 Zn finger	1305..1325	CDD:275368	10/37 (27%)
		zf-H2C2_2	1317..1341	CDD:404364	8/41 (20%)
		C2H2 Zn finger	1333..1353	CDD:275368	4/28 (14%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910