DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10348 and prdm6

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_002931772.5	Gene:	prdm6 / 100494529	XenbaseID:	XB-GENE-854907	Length:	541	Species:	Xenopus tropicalis

Alignment Length:	220	Identity:	62/220 - (28%)
Similarity:	93/220 - (42%)	Gaps:	42/220 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   189 PPQC-------SIPAVHPTLLEAMTKNLPLQYRNVFAGVLPGKVNSPAASSSPTGADFPFRHPLK 246
            |.||       ::|:   .::|||::...||..|         .|...:||......|| :.|..
Frog   322 PLQCIAQDENLNVPS---PVIEAMSRQDTLQSFN---------KNGKLSSSLQRSLVFP-QTPCN 373

  Fly   247 K----CELTWPPPTEQLQLELPHPNPKLSPVLPHPQLQDYQTRRKNKARTAATGGNATPNLPQR- 306
            :    .|.:.|..|...|:.:.:.....||........::......|.      |.......||
Frog   374 RNYSLLEKSGPLDTGYNQINVKNQRVLASPTSTSQLNSEFSDWHLWKC------GQCFKTFTQRI 432

  Fly   307 ---------NKDR-YTCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNI 361
                     |.|| |.|..|.:.|.:.:.|..|:.||:.::|:||.||.|:|:.::.|..|:|.
Frog   433 LLQMHVCTQNPDRPYQCGHCSQSFSQPSELRNHVVTHSSDRPFKCGYCGRAFAGATTLNNHIRT- 496

  Fly   362 HNKERPFKCEICERCFGQQTNLDRH 386
            |..|:|||||.|:|.|.|.|.|.||
Frog   497 HTGEKPFKCERCDRSFTQATQLSRH 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	23/73 (32%)
		zf-C2H2	311..333	CDD:278523	6/21 (29%)
		C2H2 Zn finger	313..333	CDD:275368	5/19 (26%)
		zf-H2C2_2	325..349	CDD:290200	10/23 (43%)
		C2H2 Zn finger	341..362	CDD:275368	8/20 (40%)
		zf-H2C2_2	353..377	CDD:290200	12/23 (52%)
		zf-C2H2	368..390	CDD:278523	12/19 (63%)
		C2H2 Zn finger	370..390	CDD:275368	10/17 (59%)
prdm6	XP_002931772.5	PR-SET_PRDM6	191..319	CDD:380968
		COG5048	<348..530	CDD:227381	55/191 (29%)
		C2H2 Zn finger	421..441	CDD:275368	3/25 (12%)
		C2H2 Zn finger	449..469	CDD:275368	5/19 (26%)
		zf-C2H2	475..497	CDD:395048	9/22 (41%)
		C2H2 Zn finger	477..497	CDD:275368	8/20 (40%)
		zf-H2C2_2	490..514	CDD:404364	13/24 (54%)
		C2H2 Zn finger	505..523	CDD:275368	10/17 (59%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910