DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10348 and klf12

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_002931986.2	Gene:	klf12 / 100491204	XenbaseID:	XB-GENE-980881	Length:	358	Species:	Xenopus tropicalis

Alignment Length:	392	Identity:	90/392 - (22%)
Similarity:	133/392 - (33%)	Gaps:	135/392 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 LDLRLAHKRKTDLVDQGPMEDENSNLIMFASELAV--------AQQKEKELNNNHIAASL--ADL 148
            ||...|.:.||:|::.   |..:|.:..:....||        |:..|..|:.:|.....  .||
Frog     4 LDGMPAVRVKTELLES---EQRSSKVHTYPDMEAVPLLLNNVKAEPPEDLLSTDHFQTQTEPVDL 65

  Fly   149 GFDMSRKMLRALREGGAG--GGGGGGGGGGGGGGPPNAPPLTPPQCSIPAVHPTLLEAMTKNLPL 211
            ..:.:|...|.:......  ..............|.::|.:..|..|..:| ||:|
Frog    66 SINKARTSPRGVSSSPVSITTSAASPSSNSSSSRPTSSPTVITPVPSTASV-PTVL--------- 120

  Fly   212 QYRNVFAGVLPGKVNSPAASSSPTGAD--FPFRHPLKKCELTWPPPTEQLQLELPHPNPKLS--- 271
                     .||.:   .||:|..|..  ....||:        |||..|.|:    :.|||
Frog   121 ---------TPGPL---VASASGVGGQQFLHIIHPV--------PPTSPLNLQ----SNKLSHVH 161

  Fly   272 --PVLPH---------------------PQLQDYQTRRKNKARTAATG-----------GNATPN 302
              ||:..                     |.|:|  .|...||...:.|           .:..||
Frog   162 RIPVVVQSVPVVYTAVRSPGNMNSTIVVPLLED--GRGHLKAHMDSRGLSPRLVKSDSDDDDLPN 224

  Fly   303 L---------------------------------------PQRNKDR-YTCKF--CGKVFPRSAN 325
            :                                       |...:.| :.|.|  |.||:.:|::
Frog   225 VTLDSVNETGSTALSIARAVQDSVSPFSIESTRRQRRSESPDSRRRRIHRCDFEGCNKVYTKSSH 289

  Fly   326 LTRHLRTHTGEQPYKCKY--CERSFSISSNLQRHVRNIHNKERPFKCEICERCFGQQTNLDRHLK 388
            |..|.||||||:||.|.:  |...|:.|..|.||.|. |...:||||..|:|.|.:..:|..|.:
Frog   290 LKAHRRTHTGEKPYMCTWEGCTWKFARSDELTRHYRK-HTGVKPFKCADCDRSFSRSDHLALHRR 353

  Fly   389 KH 390
            :|
Frog   354 RH 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	28/106 (26%)
		zf-C2H2	311..333	CDD:278523	9/23 (39%)
		C2H2 Zn finger	313..333	CDD:275368	9/21 (43%)
		zf-H2C2_2	325..349	CDD:290200	12/25 (48%)
		C2H2 Zn finger	341..362	CDD:275368	8/22 (36%)
		zf-H2C2_2	353..377	CDD:290200	11/23 (48%)
		zf-C2H2	368..390	CDD:278523	8/21 (38%)
		C2H2 Zn finger	370..390	CDD:275368	6/19 (32%)
klf12	XP_002931986.2	SFP1	<214..352	CDD:227516	37/138 (27%)
		C2H2 Zn finger	275..297	CDD:275368	9/21 (43%)
		C2H2 Zn finger	305..327	CDD:275368	8/22 (36%)
		zf-H2C2_2	319..344	CDD:372612	12/25 (48%)
		C2H2 Zn finger	335..355	CDD:275368	6/19 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910