DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10348 and egr3

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_002932749.1	Gene:	egr3 / 100488713	XenbaseID:	XB-GENE-976448	Length:	380	Species:	Xenopus tropicalis

Alignment Length:	411	Identity:	105/411 - (25%)
Similarity:	149/411 - (36%)	Gaps:	120/411 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 LIPTSYISHVPYDLASSASVAATSSSSTSPTTTSATTTGRLQHQHSHQQHQTLNHHAKGKRRSSF 90
            |:|.|.......||:.|.::                      :...:.||..:         .|.
Frog    16 LLPDSLYPEEGQDLSGSLAI----------------------YPGGNDQHYPV---------MST 49

  Fly    91 DQPLDLRLAH-KRKTDLVDQGPMEDENSNL-----IMFASELAVAQQKEKELNNNHIAASLADLG 149
            |..:||.|.: |...||...|..:..|..:     ..|.|..:..|:....|.::.|      ||
Frog    50 DNVIDLGLNNDKNSQDLSYNGTFQPGNKTVTYLGKFSFDSPSSWCQENIISLMSSGI------LG 108

  Fly   150 FDMSRKMLRALREGGAGGGGGGGGGGGGGGGPPNAPPLTPPQCSIPAVHPTLLEAMTKNLP---- 210
            ...|:          |..|||.|.|||.||              :...:...:|:|...||
Frog   109 VQTSQ----------APNGGGTGNGGGNGG--------------LMGQNQNDVESMFHGLPSYAG 149

  Fly   211 ---LQYRNV-FAGVLPGKVNSPAASSSPTGAD---FP-------FRHPLKKCELTWPPPTEQ--- 258
               |.:..| |.|.......|...||:....|   ||       |.|.      |..||.:|
Frog   150 CGDLYHEQVGFQGGGMAPYTSQDYSSAKQSLDSGVFPMIPDYNLFHHN------TEMPPVDQKPF 208

  Fly   259 LQLELPHPNPKLSPVLPHPQLQDYQTRRKNKARTAATGG--------------NATPNLPQR--- 306
            ..:|....||  .|:.|...::.:    |.|....:.||              ...||.|.:
Frog   209 QNMEAIRVNP--PPITPLETIKAF----KEKQVLPSFGGMGHQPPLTLKPIRPRKYPNRPSKTPL 267

  Fly   307 NKDRYTC--KFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHNKERPFK 369
            ::..:.|  :.|.:.|.||..||||||.|||.:|::|:.|.||||.|.:|..|:|. |..|:||.
Frog   268 HERPHACPAEGCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRT-HTGEKPFA 331

  Fly   370 CEICERCFGQQTNLDRHLKKH 390
            |:.|.|.|.:.....||.|.|
Frog   332 CDFCGRKFARSDERKRHAKIH 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	28/67 (42%)
		zf-C2H2	311..333	CDD:278523	11/23 (48%)
		C2H2 Zn finger	313..333	CDD:275368	11/21 (52%)
		zf-H2C2_2	325..349	CDD:290200	14/23 (61%)
		C2H2 Zn finger	341..362	CDD:275368	10/20 (50%)
		zf-H2C2_2	353..377	CDD:290200	10/23 (43%)
		zf-C2H2	368..390	CDD:278523	8/21 (38%)
		C2H2 Zn finger	370..390	CDD:275368	7/19 (37%)
egr3	XP_002932749.1	SFP1	<238..350	CDD:227516	40/112 (36%)
		C2H2 Zn finger	274..296	CDD:275368	11/21 (52%)
		COG5048	300..>352	CDD:227381	22/52 (42%)
		C2H2 Zn finger	304..324	CDD:275368	10/20 (50%)
		C2H2 Zn finger	332..352	CDD:275368	7/19 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910