DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10348 and LOC100333534

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_021322223.1	Gene:	LOC100333534 / 100333534	-ID:	-	Length:	1040	Species:	Danio rerio

Alignment Length:	308	Identity:	75/308 - (24%)
Similarity:	123/308 - (39%)	Gaps:	74/308 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   224 KVNSPAASSSPT----GADFPFRHPLKKCELTWPPPTEQLQLELPHPNPKLSPVLPHPQLQDYQT 284
            |.:|...:.|.|    |..|..:|.|          |:.:::   |...|     |:...|..::
Zfish   573 KTSSQTTAESNTCHQCGKSFAHKHYL----------TKHMRI---HTGEK-----PYTCQQCGKS 619

  Fly   285 RRKNKARTAATGGNATPNLPQRNKDR-YTCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSF 348
            .::.:        |...::...|.:: |||..|||.|....|||.|:|.||||:||.|:.|.:||
Zfish   620 FKRQE--------NLRQHMKIHNGEKLYTCHQCGKSFTWKQNLTFHMRIHTGEKPYTCQQCGKSF 676

  Fly   349 SISSNLQRHVRNIHNKERPFKCEICERCFGQQTNLDRHLKKHESDAVSLSALSGVSER----MHC 409
            :.|.||:.|:: |||.|:.:.|:.||:.|..:.||..|::.|            ..|:    .||
Zfish   677 NRSENLKEHMK-IHNGEKLYTCQKCEKSFTWKQNLTFHMRIH------------TGEKPFNCQHC 728

  Fly   410 IRRF-CENPTEESYFEEIRSFMGKV---TQQQQQQQQQQQH-DQQQQQHQSTATSASSSCSSSRD 469
            .:.| |    ::...:.:|...|:.   .|...:...::|| .:..:.|......|...|..|.
Zfish   729 EKSFTC----KQHLTDHVRMHTGEKPFNCQHCGKSFARKQHLTRHMRMHNGEKPHACLQCGKSF- 788

  Fly   470 TPTSSHEEADHAPATSTADTAAPSSSRDQEEEDSQPIMELKRTLTSKL 517
              |..|....|              .|....|:....::..:..|.||
Zfish   789 --TWKHHLVTH--------------MRIHTGEEQHSCLQCGKAFTRKL 820

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	28/63 (44%)
		zf-C2H2	311..333	CDD:278523	12/21 (57%)
		C2H2 Zn finger	313..333	CDD:275368	10/19 (53%)
		zf-H2C2_2	325..349	CDD:290200	14/23 (61%)
		C2H2 Zn finger	341..362	CDD:275368	8/20 (40%)
		zf-H2C2_2	353..377	CDD:290200	10/23 (43%)
		zf-C2H2	368..390	CDD:278523	7/21 (33%)
		C2H2 Zn finger	370..390	CDD:275368	7/19 (37%)
LOC100333534	XP_021322223.1	Merozoite_SPAM	4..>87	CDD:284533
		COG5048	72..489	CDD:227381
		C2H2 Zn finger	89..109	CDD:275368
		C2H2 Zn finger	117..137	CDD:275368
		C2H2 Zn finger	145..165	CDD:275368
		C2H2 Zn finger	173..193	CDD:275368
		C2H2 Zn finger	201..221	CDD:275368
		C2H2 Zn finger	232..252	CDD:275368
		C2H2 Zn finger	260..280	CDD:275368
		C2H2 Zn finger	288..308	CDD:275368
		C2H2 Zn finger	316..336	CDD:275368
		C2H2 Zn finger	344..364	CDD:275368
		C2H2 Zn finger	372..392	CDD:275368
		Merozoite_SPAM	500..>583	CDD:284533	2/9 (22%)
		COG5048	562..960	CDD:227381	75/308 (24%)
		C2H2 Zn finger	585..605	CDD:275368	5/32 (16%)
		C2H2 Zn finger	613..633	CDD:275368	2/27 (7%)
		C2H2 Zn finger	641..661	CDD:275368	10/19 (53%)
		C2H2 Zn finger	669..689	CDD:275368	8/20 (40%)
		C2H2 Zn finger	697..717	CDD:275368	7/19 (37%)
		C2H2 Zn finger	725..745	CDD:275368	5/23 (22%)
		C2H2 Zn finger	753..773	CDD:275368	3/19 (16%)
		C2H2 Zn finger	781..801	CDD:275368	6/36 (17%)
		C2H2 Zn finger	809..829	CDD:275368	3/12 (25%)
		C2H2 Zn finger	837..857	CDD:275368
		C2H2 Zn finger	868..888	CDD:275368
		C2H2 Zn finger	896..916	CDD:275368
		C2H2 Zn finger	924..942	CDD:275368
		C2H2 Zn finger	952..972	CDD:275368
		zf-H2C2_2	964..989	CDD:316026
		C2H2 Zn finger	980..1000	CDD:275368
		C2H2 Zn finger	1008..1028	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910