DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10348 and LOC100331219

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_021331297.1	Gene:	LOC100331219 / 100331219	-ID:	-	Length:	440	Species:	Danio rerio

Alignment Length:	250	Identity:	66/250 - (26%)
Similarity:	100/250 - (40%)	Gaps:	33/250 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   276 HPQLQDYQTRRKNKARTAATGGNATPNLPQRNKDR-YTCKFCGKVFPRSANLTRHLRTHTGEQPY 339
            |.:.:.|...:..|:.|...|  .|.::.....:| |||:.|.|.|....|...|:|.||||:||
Zfish   151 HTKERPYTCEQCGKSFTYKQG--FTTHMRIHTGERPYTCQQCKKSFYHPGNFAVHMRIHTGERPY 213

  Fly   340 KCKYCERSFSISSNLQRHVRNIHNKERPFKCEICERCFGQQTNLDRHLKKHESDAVSLSALSG-- 402
            .|:.|.:||..|.|...|:| ||..|||:.|..|.:.|.|...|:.|::.|..|...:....|
Zfish   214 TCQQCGKSFYQSGNFAAHMR-IHTGERPYSCIQCGKSFKQNGTLEVHMRTHTGDRSFICTHCGKH 277

  Fly   403 --------VSERMH----------CIRRFCENPTEESYFEEIRSFMGKVTQQQQQQQQQQQHDQQ 449
                    :..|:|          |.:||.:   :.|....:|...|:...:..:..:...|...
Zfish   278 FSQKHDLNIHVRIHTGEKPHTCTQCGKRFIQ---KTSLGNHMRIHTGEKPYRCTECGKTFPHKST 339

  Fly   450 QQQHQSTATS----ASSSCSSSRDTPTSSHEEADHAPAT--STADTAAPSSSRDQ 498
            .:.|..|.|.    |.:.|.....|..|.....|:...|  .|.|....|.:|.:
Zfish   340 LKHHMRTHTGEKPFACAQCGKRFTTKASLKNLMDNHTGTIVLTCDQCEKSLTRKE 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	26/63 (41%)
		zf-C2H2	311..333	CDD:278523	9/21 (43%)
		C2H2 Zn finger	313..333	CDD:275368	7/19 (37%)
		zf-H2C2_2	325..349	CDD:290200	12/23 (52%)
		C2H2 Zn finger	341..362	CDD:275368	8/20 (40%)
		zf-H2C2_2	353..377	CDD:290200	10/23 (43%)
		zf-C2H2	368..390	CDD:278523	6/21 (29%)
		C2H2 Zn finger	370..390	CDD:275368	6/19 (32%)
LOC100331219	XP_021331297.1	COG5048	73..440	CDD:227381	66/249 (27%)
		C2H2 Zn finger	103..123	CDD:275368
		C2H2 Zn finger	131..151	CDD:275368	66/249 (27%)
		C2H2 Zn finger	159..179	CDD:275368	4/21 (19%)
		C2H2 Zn finger	187..207	CDD:275368	7/19 (37%)
		C2H2 Zn finger	215..235	CDD:275368	8/20 (40%)
		C2H2 Zn finger	243..263	CDD:275368	6/19 (32%)
		C2H2 Zn finger	271..291	CDD:275368	2/19 (11%)
		C2H2 Zn finger	299..319	CDD:275368	5/22 (23%)
		C2H2 Zn finger	327..347	CDD:275368	2/19 (11%)
		C2H2 Zn finger	412..432	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910