DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10348 and znf711

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_001161471.2	Gene:	znf711 / 100124306	XenbaseID:	XB-GENE-956382	Length:	807	Species:	Xenopus tropicalis

Alignment Length:	164	Identity:	46/164 - (28%)
Similarity:	80/164 - (48%)	Gaps:	25/164 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   238 DFPFRHPLKKCELTWPPPTEQLQLELPHPNPKLSPVLPHPQLQDYQTRR---KNKARTAATG--- 296
            |||  |....|:..:..|:|..:....|...|:           :|.|.   |.......:|
Frog   662 DFP--HKCDVCDKGFHRPSEMKKHSETHKGKKI-----------HQCRHCDFKTSDPFILSGHIL 713

  Fly   297 GNATPNLPQRNKDRYTCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNI 361
            ...|.:||      :.||.|.:.|.....|.:|::||:|::.|:|:|||.|.:.:|..:|||.:|
Frog   714 SVHTKDLP------FKCKKCKRGFRIQPELKKHMKTHSGKKVYQCQYCEYSTTDASGFKRHVISI 772

  Fly   362 HNKERPFKCEICERCFGQQTNLDRHLKKHESDAV 395
            |.|:.|.:||.|::.|.:.:..::|:.:|..:|:
Frog   773 HTKDYPHRCEFCKKGFRRPSEKNQHIMRHHKEAL 806

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	23/62 (37%)
		zf-C2H2	311..333	CDD:278523	6/21 (29%)
		C2H2 Zn finger	313..333	CDD:275368	6/19 (32%)
		zf-H2C2_2	325..349	CDD:290200	11/23 (48%)
		C2H2 Zn finger	341..362	CDD:275368	9/20 (45%)
		zf-H2C2_2	353..377	CDD:290200	10/23 (43%)
		zf-C2H2	368..390	CDD:278523	5/21 (24%)
		C2H2 Zn finger	370..390	CDD:275368	5/19 (26%)
znf711	NP_001161471.2	Zfx_Zfy_act	65..414	CDD:368066
		COG5048	<422..600	CDD:227381
		C2H2 Zn finger	431..451	CDD:275368
		C2H2 Zn finger	524..545	CDD:275368
		zf-C2H2	551..573	CDD:333835
		C2H2 Zn finger	553..573	CDD:275368
		zf-H2C2_2	565..589	CDD:372612
		C2H2 Zn finger	581..602	CDD:275368
		COG5048	<587..768	CDD:227381	32/124 (26%)
		C2H2 Zn finger	610..626	CDD:275368
		C2H2 Zn finger	638..659	CDD:275368
		C2H2 Zn finger	667..687	CDD:275368	3/19 (16%)
		C2H2 Zn finger	724..744	CDD:275368	6/19 (32%)
		C2H2 Zn finger	752..773	CDD:275368	9/20 (45%)
		C2H2 Zn finger	781..801	CDD:275368	5/19 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910