DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10348 and zgc:172128

DIOPT Version :9

Sequence 1:	NP_001286059.1	Gene:	CG10348 / 35132	FlyBaseID:	FBgn0032707	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_001107945.1	Gene:	zgc:172128 / 100002012	ZFINID:	ZDB-GENE-080220-2	Length:	442	Species:	Danio rerio

Alignment Length:	177	Identity:	55/177 - (31%)
Similarity:	82/177 - (46%)	Gaps:	39/177 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   261 LELP---HPNPKLSPVLPHPQLQDYQTRRKNKARTAATGGNATPNLPQ----------------R 306
            ||:|   |...|  |.|......:|.|::..:.......|. .|::.|                |
Zfish   150 LEVPMRIHTGTK--PYLCQQCGNNYTTKQNIEVHMRTHTGR-KPHICQECGVSFIYKTSLEEHMR 211

  Fly   307 NKDR---YTCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHNKERPF 368
            |..|   :||:.||..|....||..|:.|||||:|:.|:.|.:.|:..|||:.|:| ||.:|||:
Zfish   212 NHPRLKPFTCQQCGNRFTTKRNLEDHMITHTGEKPFTCELCGKGFTTKSNLKVHMR-IHTEERPY 275

  Fly   369 KCEICERCFGQQTNLDRHLKKHESDAVSLSALSGVSERMHCIRRFCE 415
            .||.|||.|.::.:|:.|.:.|            ::|:.|.... ||
Zfish   276 TCEQCERSFTRKDSLESHRRMH------------MAEKSHACPH-CE 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10348	NP_001286059.1	COG5048	300..>363	CDD:227381	28/81 (35%)
		zf-C2H2	311..333	CDD:278523	8/21 (38%)
		C2H2 Zn finger	313..333	CDD:275368	7/19 (37%)
		zf-H2C2_2	325..349	CDD:290200	11/23 (48%)
		C2H2 Zn finger	341..362	CDD:275368	8/20 (40%)
		zf-H2C2_2	353..377	CDD:290200	14/23 (61%)
		zf-C2H2	368..390	CDD:278523	8/21 (38%)
		C2H2 Zn finger	370..390	CDD:275368	8/19 (42%)
zgc:172128	NP_001107945.1	COG5048	63..435	CDD:227381	55/177 (31%)
		C2H2 Zn finger	81..101	CDD:275368
		C2H2 Zn finger	109..129	CDD:275368
		zf-H2C2_2	121..146	CDD:290200
		UNC-79	<136..>246	CDD:291442	28/98 (29%)
		C2H2 Zn finger	137..157	CDD:275368	3/6 (50%)
		C2H2 Zn finger	165..185	CDD:275368	2/19 (11%)
		C2H2 Zn finger	193..213	CDD:275368	2/19 (11%)
		C2H2 Zn finger	221..241	CDD:275368	7/19 (37%)
		zf-H2C2_2	233..258	CDD:290200	12/24 (50%)
		C2H2 Zn finger	249..269	CDD:275368	8/20 (40%)
		zf-H2C2_2	261..286	CDD:290200	15/25 (60%)
		C2H2 Zn finger	277..297	CDD:275368	8/19 (42%)
		C2H2 Zn finger	305..322	CDD:275368	2/6 (33%)
		C2H2 Zn finger	333..353	CDD:275368
		C2H2 Zn finger	361..381	CDD:275368
		C2H2 Zn finger	389..409	CDD:275368
		zf-H2C2_2	401..426	CDD:290200
		C2H2 Zn finger	417..437	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910