Protein Alignment Irk3 and Kcnj11

DIOPT Version :9

• Sequence 1: NP_001137835.2
• Gene: Irk3 / 35131
• FlyBaseID: FBgn0032706
• Length: 446
• Species: Drosophila melanogaster
• Sequence 2: NP_112648.2
• Gene: Kcnj11 / 83535
• RGDID: 69247
• Length: 390
• Species: Rattus norvegicus
• Alignment Length: 370
• Identity: 123/370 - (33%)
• Similarity: 196/370 - (52%)
• Gaps: 42/370 - (11%)

  Fly    68 DHLETRSEQNPTFSFPYAHDWAGSTIELTPDLGSGPRTSSSDGLRRSLNRVMEKNGKENVVFRRI 132
            :::.||..::||                      .||..:.:  ||:  |.:.|.|..||..:.|
  Rat    11 EYVLTRLAEDPT----------------------EPRYRTRE--RRA--RFVSKKGNCNVAHKNI 49

  Fly   133 PEKSWRYMRDLVTTLMELEWKYMLTLFLGSYFLSWLLFAALCYVVAYSHGDFIFDPVSGKRMGEG 197
            .|:. |:::|:.|||::|:|.:.|.:|..|:..||||||.:.:::|::|||.        ..|||
  Rat    50 REQG-RFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFAMVWWLIAFAHGDL--------APGEG 105

  Fly   198 VD-PCIYGVHSWVAMIIYSVETQTTLGFGEKYASEECPETIFLFVMQMLSAALIEGCMVSVIYAK 261
            .: ||:..:||:.:..::|:|.|.|:|||.:..:||||..|.:.::|.:...:|...|:..|:.|
  Rat   106 TNVPCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAILILIVQNIVGLMINAIMLGCIFMK 170

  Fly   262 TARPARQLTKLKFSDKAVICYRDGRLCLLFRVCDPREQQSIESKIRVYIIVDKRTREGETIKSH- 325
            ||:..|:...|.||..|||..|.||||.:.||.|.|:...|.:.|.:.::....:.|||.:..|
  Rat   171 TAQAHRRAETLIFSKHAVITLRHGRLCFMLRVGDLRKSMIISATIHMQVVRKTTSPEGEVVPLHQ 235

  Fly   326 VELKLE---GNGEQIILWPDVVCHVIDETSPLSQFTTAKLFNAAQFELYVSIVGTSPATAQMTEA 387
            |::.:|   |.....::.|.::.||||..|||.....:.|.:....|:.|.:.|....|...|:|
  Rat   236 VDIPMENGVGGNSIFLVAPLIIYHVIDSNSPLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQA 300

  Fly   388 KTSYLPREIFWGQRFVNIIHYDAQNERYIVDYENFNRTISVDMPM 432
            :||||..||.||||||.|:  ..::.||.|||..|..|:.|..|:
  Rat   301 RTSYLADEILWGQRFVPIV--AEEDGRYSVDYSKFGNTVKVPTPL 343

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk3	NP_001137835.2	Ion_trans_2	119..432	CDD:304432	113/317 (36%)
Kcnj11	NP_112648.2	IRK	36..356	CDD:279361	114/319 (36%)
		Selectivity filter. /evidence=ECO:0000250	130..135		3/4 (75%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346795
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D289862at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11767
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.950