Protein Alignment Irk3 and kcnj12b

DIOPT Version :9

• Sequence 1: NP_001137835.2
• Gene: Irk3 / 35131
• FlyBaseID: FBgn0032706
• Length: 446
• Species: Drosophila melanogaster
• Sequence 2: XP_001335950.1
• Gene: kcnj12b / 795702
• ZFINID: ZDB-GENE-091118-79
• Length: 421
• Species: Danio rerio
• Alignment Length: 374
• Identity: 124/374 - (33%)
• Similarity: 204/374 - (54%)
• Gaps: 23/374 - (6%)

  Fly    83 PYAHDWAGSTIE------LTPDLGSGPRTSSSDGLRRSLNRVMEKNGKENVVFRRIPEKSWRYMR 141
            |:.::...|:.|      ..|.||:|.........|:..:|.:.|.|:.||.|..:.|:|.||:.
Zfish     6 PHRYNIVSSSEEDVGRHGTMPALGNGFGNGKIQTRRKLRSRFVNKTGQCNVSFAHMDEQSQRYLA 70

  Fly   142 DLVTTLMELEWKYMLTLFLGSYFLSWLLFAALCYVVAYSHGDFIFDPVSGKRMGEGVDPCIYGVH 206
            |:.||.::..|::|..||..::.:|||.|....:::|..|||.       ::..|...||:..|:
Zfish    71 DIFTTCVDSRWRWMFLLFSLAFVISWLAFGFAFWLIALVHGDL-------EKPQENFTPCVMQVN 128

  Fly   207 SWVAMIIYSVETQTTLGFGEKYASEECPETIFLFVMQMLSAALIEGCMVSVIYAKTARPARQLTK 271
            |:||..::|||||||:|:|.:..:||||..:|:.|.|.:...:|:..|:..|.||.|||.::...
Zfish   129 SFVAAFLFSVETQTTIGYGFRCVTEECPLAVFMVVFQSIVGCIIDSFMIGAIMAKMARPKKRAET 193

  Fly   272 LKFSDKAVICYRDGRLCLLFRVCDPREQQSIESKIRVYIIVDKRTREGETIK-SHVELKL---EG 332
            :.||..|||..|||:|||::||.:.|:...:|:.:|..:|..:.|.|||.|. ..:::.:   :|
Zfish   194 ILFSHNAVISMRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRITEEGEYIPLDQIDINVGYDQG 258

  Fly   333 NGEQIILWPDVVCHVIDETSPLSQFTTAKLFNAAQFELYVSIVGTSPATAQMTEAKTSYLPREIF 397
            .....::.|..:.|.|:|.|||.......| ..:.||:.|.:.|...|||...:.::|||..||.
Zfish   259 LDRIFLVAPLTILHEINEESPLFGINQQDL-ETSDFEIVVILEGMVEATAMTAQVRSSYLSSEIL 322

  Fly   398 WGQRFVNIIHYDAQNERYIVDYENFNRTISV-DMPMTNPKN--DHLKLE 443
            ||.||..:: ::.:|: |.|||.:|::|..| ..|..:.|:  |:..||
Zfish   323 WGHRFEPVV-FEERNQ-YKVDYSHFHKTYEVPSTPRCSAKDLEDNKSLE 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk3	NP_001137835.2	Ion_trans_2	119..432	CDD:304432	110/317 (35%)
kcnj12b	XP_001335950.1	IRK_N	2..47	CDD:312087	8/40 (20%)
		IRK	48..367	CDD:307239	113/328 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D289862at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11767
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.020