Protein Alignment Irk3 and kcnj11

DIOPT Version :9

• Sequence 1: NP_001137835.2
• Gene: Irk3 / 35131
• FlyBaseID: FBgn0032706
• Length: 446
• Species: Drosophila melanogaster
• Sequence 2: NP_001034916.1
• Gene: kcnj11 / 664687
• ZFINID: ZDB-GENE-060308-2
• Length: 381
• Species: Danio rerio
• Alignment Length: 324
• Identity: 104/324 - (32%)
• Similarity: 176/324 - (54%)
• Gaps: 15/324 - (4%)

  Fly   117 RVMEKNGKENVVFRRIPEKSWRYMRDLVTTLMELEWKYMLTLFLGSYFLSWLLFAALCYVVAYSH 181
            |.:.|||..||....|.|:. |:::|:.|||::|:|.:.|.:|..|:..|||||..:.:::|::|
Zfish    34 RFVAKNGTCNVAHTNIREQG-RFLQDVFTTLVDLKWLHTLVIFTMSFLCSWLLFGMIWWLIAFAH 97

  Fly   182 GDFIFDPVSGKRMGEGVDPCIYGVHSWVAMIIYSVETQTTLGFGEKYASEECPETIFLFVMQMLS 246
            ||.       ...||...||:..:||:.:..::|:|.|.|:|||.:..:|||...|.:.::|.:.
Zfish    98 GDL-------DLKGEDFVPCVTDIHSFSSAFLFSIEVQVTIGFGGRMITEECVSAIVILILQNIV 155

  Fly   247 AALIEGCMVSVIYAKTARPARQLTKLKFSDKAVICYRDGRLCLLFRVCDPREQQSIESKIRVYII 311
            ..:|...|:..|:.|||:..|:...|.||..|||..|:.:||.:||:.|.|:...|.:.:.:.::
Zfish   156 GLVINAIMLGCIFMKTAQANRRAETLIFSKHAVITVRNNKLCFMFRLGDLRKSMIISATVHMQVV 220

  Fly   312 VDKRTREGETIK-SHVELKLE---GNGEQIILWPDVVCHVIDETSPLSQFTTAKLFNAAQFELYV 372
            ....|.|||.:. ..::::::   |.....::.|.::.|.||:.|||...:...|.: ...|:.|
Zfish   221 RKTVTSEGEMVPLDQIDIQMDNPVGTNSIFLVSPLIISHTIDKNSPLYDLSADDLLH-EDIEVIV 284

  Fly   373 SIVGTSPATAQMTEAKTSYLPREIFWGQRFVNIIHYDAQNERYIVDYENFNRTISVDMPMTNPK 436
            .:.|....|...|:|:||||..||.||.|||..:  ..::..|.|||..|..|:.|..|.::.:
Zfish   285 VLEGVVETTGITTQARTSYLSEEILWGHRFVPTV--SEEDGMYAVDYSKFGNTVKVATPNSSAR 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk3	NP_001137835.2	Ion_trans_2	119..432	CDD:304432	102/316 (32%)
kcnj11	NP_001034916.1	IRK	36..362	CDD:279361	103/322 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588253
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D289862at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11767
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.950