Protein Alignment Irk3 and kcnj1a.4

DIOPT Version :9

• Sequence 1: NP_001137835.2
• Gene: Irk3 / 35131
• FlyBaseID: FBgn0032706
• Length: 446
• Species: Drosophila melanogaster
• Sequence 2: NP_001038643.1
• Gene: kcnj1a.4 / 569191
• ZFINID: ZDB-GENE-050420-186
• Length: 368
• Species: Danio rerio
• Alignment Length: 345
• Identity: 105/345 - (30%)
• Similarity: 175/345 - (50%)
• Gaps: 28/345 - (8%)

  Fly   112 RRSLNRVMEKNGKENVVFRRIPEKS-WRYMRDLVTTLMELEWKYMLTLFLGSYFLSWLLFAALCY 175
            |....||:.|:|:.|:.|..:..:: :.|:.|..|||:|..|::::..|:.||.|||.:|..|.|
Zfish    17 RSHKKRVVTKDGRCNIKFGNVMHRNRFTYVLDFWTTLVETRWRFIIFYFVASYTLSWFIFGLLWY 81

  Fly   176 VVAYSHGDFIF-DPVSGKRMGEGVDPCIYGVHSWVAMIIYSVETQTTLGFGEKYASEECPETIFL 239
            .:|.|:||.:: :|....      :||.|.::......:||:|||.|:|:|..|.:::||..:.|
Zfish    82 WLARSNGDLLWQNPPPDH------NPCAYSLNGMTYAFLYSLETQGTVGYGNVYVTDQCPGGVAL 140

  Fly   240 FVMQMLSAALIEGCMVSVIYAKTARPARQLTKLKFSDKAVICYRDGRLCLLFRVCDPREQQSIES 304
            .::||:....|......::..|...|.::...:.||:.||||.:.|.|||..||.:.|:...|.|
Zfish   141 IIIQMIVGLFIRIFWGGIVITKITLPKKRAKTITFSESAVICPKKGTLCLQIRVANLRKTLMIGS 205

  Fly   305 KIRVYIIVDKRT--REGET-IKSHVELKL---EGNGEQIILWPDVVCHVIDETSPLSQFTTAKLF 363
            :|...::   ||  ..||| |...|.:..   .|......:.|..:.|:||::||........:
Zfish   206 QIYGKLL---RTTITGGETNILDQVSINFMVDAGKDNLFFVCPLTLYHIIDKSSPFFDMAVDTM- 266

  Fly   364 NAAQFELYVSIVGTSPATAQMTEAKTSYLPREIFWGQRFVNIIHYDAQNERYIVDYENFNRTISV 428
            :...|||.|.:.|.:..|:...:.:|||:|:||.||..|:.||....:. :|.||:.||.:.:.|
Zfish   267 HQQDFELVVFLDGMAETTSSSCQVRTSYIPQEIMWGYDFLPIISRSKEG-KYRVDFSNFTKVVPV 330

  Fly   429 DMPMT-------NPKNDHLK 441
              |..       |...:||:
Zfish   331 --PTAHCSRCYHNEPGNHLE 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk3	NP_001137835.2	Ion_trans_2	119..432	CDD:304432	98/320 (31%)
kcnj1a.4	NP_001038643.1	IRK	24..352	CDD:279361	102/338 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588247
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D289862at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11767
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.040