Protein Alignment Irk3 and Kcnj1

DIOPT Version :9

• Sequence 1: NP_001137835.2
• Gene: Irk3 / 35131
• FlyBaseID: FBgn0032706
• Length: 446
• Species: Drosophila melanogaster
• Sequence 2: NP_001161826.1
• Gene: Kcnj1 / 56379
• MGIID: 1927248
• Length: 392
• Species: Mus musculus
• Alignment Length: 346
• Identity: 111/346 - (32%)
• Similarity: 188/346 - (54%)
• Gaps: 21/346 - (6%)

  Fly   110 GLRRSLNRVMEKNGKENVVFRRIPEKS-WRYMRDLVTTLMELEWKYMLTLFLGSYFLSWLLFAAL 173
            |..|...|::.|:|:.|:.|..:..:| :.:..|:.||:::|:|:|.:|:|:.::..||.||..|
Mouse    35 GRSRQRARLVSKDGRCNIEFGNVDAQSRFIFFVDIWTTVLDLKWRYKMTVFITAFLGSWFLFGLL 99

  Fly   174 CYVVAYSHGDF--IFDPVSGKRMGEGVDPCIYGVHSWVAMIIYSVETQTTLGFGEKYASEECPET 236
            .|||||.|.|.  .:.|       :...||:..::...:..::|:|||.|:|:|.::.:|:|...
Mouse   100 WYVVAYVHKDLPEFYPP-------DNRTPCVENINGMTSAFLFSLETQVTIGYGFRFVTEQCATA 157

  Fly   237 IFLFVMQMLSAALIEGCMVSVIYAKTARPARQLTKLKFSDKAVICYRDGRLCLLFRVCDPREQQS 301
            |||.:.|.:...:|...|...|.||.:||.::...:.||..|||..|.|:||||.||.:.|:...
Mouse   158 IFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANLRKSLL 222

  Fly   302 IESKIRVYIIVDKRTREGETI---KSHVELKLE-GNGEQIILWPDVVCHVIDETSPLSQFTTAKL 362
            |.|.|...::....|.|||||   ::::...:: ||.....:.|..:.|:||..||.... .|:.
Mouse   223 IGSHIYGKLLKTTITPEGETIILDQTNINFVVDAGNENLFFISPLTIYHIIDHNSPFFHM-AAET 286

  Fly   363 FNAAQFELYVSIVGTSPATAQMTEAKTSYLPREIFWGQRFVNIIHYDAQNERYIVDYENFNRTIS 427
            .:...|||.|.:.||..:|:...:.:|||:|.|:.||.|||.|:. ..:..:|.||:.||.:|:.
Mouse   287 LSQQDFELVVFLDGTVESTSATCQVRTSYIPEEVLWGYRFVPIVS-KTKEGKYRVDFHNFGKTVE 350

  Fly   428 VDMP-----MTNPKNDHLKLE 443
            |:.|     :.|.|:...:::
Mouse   351 VETPHCAMCLYNEKDARARMK 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk3	NP_001137835.2	Ion_trans_2	119..432	CDD:304432	106/324 (33%)
Kcnj1	NP_001161826.1	IRK	44..372	CDD:279361	108/337 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843281
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D289862at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11767
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.950