Protein Alignment Irk3 and KCNJ16

DIOPT Version :9

• Sequence 1: NP_001137835.2
• Gene: Irk3 / 35131
• FlyBaseID: FBgn0032706
• Length: 446
• Species: Drosophila melanogaster
• Sequence 2: XP_005257394.1
• Gene: KCNJ16 / 3773
• HGNCID: 6262
• Length: 453
• Species: Homo sapiens
• Alignment Length: 325
• Identity: 102/325 - (31%)
• Similarity: 181/325 - (55%)
• Gaps: 12/325 - (3%)

  Fly   112 RRSLNRVMEKNGKENVVFRRIPEKSWRYMRDLVTTLMELEWKYMLTLFLGSYFLSWLLFAALCYV 176
            ||:..|::.|:|..||.|:.|..:...|:.|:.|||::.:|::|..:|..||.||||:|.::.::
Human    65 RRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFGSVFWL 129

  Fly   177 VAYSHGDFIFDPVSGKRMGEGVDPCIYGVHSWVAMIIYSVETQTTLGFGEKYASEECPETIFLFV 241
            :|:.|||.:.||        .:.||:..|||:....::|:|||||:|:|.:..:|||...:.:.:
Human   130 IAFHHGDLLNDP--------DITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVAVLMVI 186

  Fly   242 MQMLSAALIEGCMVSVIYAKTARPARQLTKLKFSDKAVICYRDGRLCLLFRVCDPREQQSIESKI 306
            :|.:.:.:|...::....||.|...::...::||..|:|..|||:|||::|:.|.|....:|..:
Human   187 LQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRPNHVVEGTV 251

  Fly   307 RVYIIVDKRTREGETIKSHVELKLEGNGEQIILWPDVVCHVIDETSPLSQFTTAKLFNAAQFELY 371
            |..::......||....:..:|||. |.:.|::.|..:.|.||..|||... ..|......||:.
Human   252 RAQLLRYTEDSEGRMTMAFKDLKLV-NDQIILVTPVTIVHEIDHESPLYAL-DRKAVAKDNFEIL 314

  Fly   372 VSIVGTSPATAQMTEAKTSYLPREIFWGQRFVNIIHYDAQNERYIVDYENFNRTISVDMPMTNPK 436
            |:.:.|..:|....::::||:||||.||.||.:::  :.:.:.|.|:...|..::.|..|..:.|
Human   315 VTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVL--EVKRKYYKVNCLQFEGSVEVYAPFCSAK 377

  Fly   437  436
            Human   378  377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk3	NP_001137835.2	Ion_trans_2	119..432	CDD:304432	97/312 (31%)
KCNJ16	XP_005257394.1	IRK	72..387	CDD:279361	99/318 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D289862at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11767
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.020