Protein Alignment Irk3 and Kcnj16

DIOPT Version :9

• Sequence 1: NP_001137835.2
• Gene: Irk3 / 35131
• FlyBaseID: FBgn0032706
• Length: 446
• Species: Drosophila melanogaster
• Sequence 2: NP_445766.2
• Gene: Kcnj16 / 29719
• RGDID: 61824
• Length: 419
• Species: Rattus norvegicus
• Alignment Length: 325
• Identity: 104/325 - (32%)
• Similarity: 180/325 - (55%)
• Gaps: 12/325 - (3%)

  Fly   112 RRSLNRVMEKNGKENVVFRRIPEKSWRYMRDLVTTLMELEWKYMLTLFLGSYFLSWLLFAALCYV 176
            ||:..|::.|:|..||.|:.|..:...||.|:.|||::.:|::|..:|..||.||||:|.::.::
  Rat    30 RRARRRLLHKDGSCNVYFKHIFGEWGSYMVDIFTTLVDTKWRHMFVIFSLSYILSWLIFGSIFWL 94

  Fly   177 VAYSHGDFIFDPVSGKRMGEGVDPCIYGVHSWVAMIIYSVETQTTLGFGEKYASEECPETIFLFV 241
            :|..|||.:.||        .:.||:..|||:.|..::|:|||||:|:|.:..:|||...:...:
  Rat    95 IALHHGDLLSDP--------DITPCVDNVHSFTAAFLFSLETQTTIGYGYRCVTEECSVAVLTVI 151

  Fly   242 MQMLSAALIEGCMVSVIYAKTARPARQLTKLKFSDKAVICYRDGRLCLLFRVCDPREQQSIESKI 306
            :|.:.:.:|...::....||.|...::...::||..|:|..|||:|||::|:.|.|....:|..:
  Rat   152 LQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRPNHVVEGTV 216

  Fly   307 RVYIIVDKRTREGETIKSHVELKLEGNGEQIILWPDVVCHVIDETSPLSQFTTAKLFNAAQFELY 371
            |..::......||....:..:|||. |.:.|::.|..:.|.||..|||... ..|......||:.
  Rat   217 RAQLLRYSEDSEGRMTMAFKDLKLV-NDQIILVTPVTIVHEIDHESPLYAL-DRKAVAKDNFEIL 279

  Fly   372 VSIVGTSPATAQMTEAKTSYLPREIFWGQRFVNIIHYDAQNERYIVDYENFNRTISVDMPMTNPK 436
            |:.:.|..:|....::::||:||||.||.||.:::  :.:.:.|.|:...|..::.|..|..:.|
  Rat   280 VTFIYTGDSTGTSHQSRSSYVPREILWGHRFHDVL--EVKRKYYKVNCLQFEGSVEVYAPFCSAK 342

  Fly   437  436
              Rat   343  342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk3	NP_001137835.2	Ion_trans_2	119..432	CDD:304432	99/312 (32%)
Kcnj16	NP_445766.2	IRK	37..173	CDD:395797	49/143 (34%)
		Selectivity filter. /evidence=ECO:0000250	131..136		2/4 (50%)
		IRK_C	182..349	CDD:407551	51/165 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D289862at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11767
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.020