Protein Alignment Irk3 and Kcnj1

DIOPT Version :9

• Sequence 1: NP_001137835.2
• Gene: Irk3 / 35131
• FlyBaseID: FBgn0032706
• Length: 446
• Species: Drosophila melanogaster
• Sequence 2: NP_058719.2
• Gene: Kcnj1 / 24521
• RGDID: 2957
• Length: 391
• Species: Rattus norvegicus
• Alignment Length: 346
• Identity: 111/346 - (32%)
• Similarity: 187/346 - (54%)
• Gaps: 21/346 - (6%)

  Fly   110 GLRRSLNRVMEKNGKENVVFRRIPEKS-WRYMRDLVTTLMELEWKYMLTLFLGSYFLSWLLFAAL 173
            |..|...|::.|.|:.|:.|..:..:| :.:..|:.||:::|:|:|.:|:|:.::..||.||..|
  Rat    34 GRSRQRARLVSKEGRCNIEFGNVDAQSRFIFFVDIWTTVLDLKWRYKMTVFITAFLGSWFLFGLL 98

  Fly   174 CYVVAYSHGDF--IFDPVSGKRMGEGVDPCIYGVHSWVAMIIYSVETQTTLGFGEKYASEECPET 236
            .|||||.|.|.  .:.|       :...||:..::...:..::|:|||.|:|:|.::.:|:|...
  Rat    99 WYVVAYVHKDLPEFYPP-------DNRTPCVENINGMTSAFLFSLETQVTIGYGFRFVTEQCATA 156

  Fly   237 IFLFVMQMLSAALIEGCMVSVIYAKTARPARQLTKLKFSDKAVICYRDGRLCLLFRVCDPREQQS 301
            |||.:.|.:...:|...|...|.||.:||.::...:.||..|||..|.|:||||.||.:.|:...
  Rat   157 IFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANLRKSLL 221

  Fly   302 IESKIRVYIIVDKRTREGETI---KSHVELKLE-GNGEQIILWPDVVCHVIDETSPLSQFTTAKL 362
            |.|.|...::....|.|||||   ::::...:: ||.....:.|..:.|:||..||.... .|:.
  Rat   222 IGSHIYGKLLKTTITPEGETIILDQTNINFVVDAGNENLFFISPLTIYHIIDHNSPFFHM-AAET 285

  Fly   363 FNAAQFELYVSIVGTSPATAQMTEAKTSYLPREIFWGQRFVNIIHYDAQNERYIVDYENFNRTIS 427
            .:...|||.|.:.||..:|:...:.:|||:|.|:.||.|||.|:. ..:..:|.||:.||.:|:.
  Rat   286 LSQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFVPIVS-KTKEGKYRVDFHNFGKTVE 349

  Fly   428 VDMP-----MTNPKNDHLKLE 443
            |:.|     :.|.|:...:::
  Rat   350 VETPHCAMCLYNEKDARARMK 370

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk3	NP_001137835.2	Ion_trans_2	119..432	CDD:304432	106/324 (33%)
Kcnj1	NP_058719.2	IRK	43..371	CDD:279361	108/337 (32%)
		Selectivity filter. /evidence=ECO:0000250	141..146		2/4 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346792
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D289862at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11767
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.950