Protein Alignment Irk3 and irk-2

DIOPT Version :9

• Sequence 1: NP_001137835.2
• Gene: Irk3 / 35131
• FlyBaseID: FBgn0032706
• Length: 446
• Species: Drosophila melanogaster
• Sequence 2: NP_001368610.1
• Gene: irk-2 / 191695
• WormBaseID: WBGene00002150
• Length: 497
• Species: Caenorhabditis elegans
• Alignment Length: 340
• Identity: 119/340 - (35%)
• Similarity: 191/340 - (56%)
• Gaps: 20/340 - (5%)

  Fly    96 TPDLGSGPRTSSSDGLRRSLNRVMEKNGKENVVFRRIPEKSWRYMRDLVTTLMELEWKYMLTLFL 160
            ||.||         |.||..||:::|.|..|:..:.:|::..:|..|:.||::|::|::.|..|.
 Worm    52 TPRLG---------GSRRIRNRLVQKQGLCNISLKNVPKQRRKYFSDIFTTVIEMKWRWCLLYFS 107

  Fly   161 GSYFLSWLLFAALCYVVAYSHGDFIFDPVSGKRMGEGVDPCIYGVHSWVAMIIYSVETQTTLGFG 225
            .|:.:||..||.:.:::|..|||  .:.::....    .|||..||:.:...::|..||||:|:|
 Worm   108 LSFMISWSFFATVYFLIAKQHGD--IEQIANATW----TPCIVNVHNELNAFLFSFTTQTTIGYG 166

  Fly   226 EKYASEECPETIFLFVMQMLSAALIEGCMVSVIYAKTARPARQLTKLKFSDKAVICYRDGRLCLL 290
            .:|.::.||.||.....|.:...:.:..|..:|::|.|||.::...|.||..||||.|||:||||
 Worm   167 FRYPTDACPLTIVTMCFQFMWGVMTQTLMAGIIFSKLARPIKRAATLIFSKNAVICLRDGKLCLL 231

  Fly   291 FRVCDPREQQSIESKIRVYIIVDKRTREGETIKSH-VELKL---EGNGEQIILWPDVVCHVIDET 351
            |||.|.|:....|:.:|:.:|....|.|||.:..| .::.:   :|.....::||..:||.|||.
 Worm   232 FRVGDMRKSSLAEAHVRLQMIKRCVTYEGELLPFHQFDMDVGYDQGLDRVFVIWPITICHEIDER 296

  Fly   352 SPLSQFTTAKLFNAAQFELYVSIVGTSPATAQMTEAKTSYLPREIFWGQRFVNIIHYDAQNERYI 416
            |||.:.....| .:|:||:...:.|...:....|:|:|||||.||.||.||..::||..:|.:|.
 Worm   297 SPLWEIGADDL-KSAKFEIIAILEGVVESVGSTTQARTSYLPSEILWGHRFEKLVHYKKENGQYN 360

  Fly   417 VDYENFNRTISVDMP 431
            :|:..|:...||:.|
 Worm   361 IDFGKFHNVYSVNTP 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk3	NP_001137835.2	Ion_trans_2	119..432	CDD:304432	110/317 (35%)
irk-2	NP_001368610.1	IRK	66..206	CDD:395797	43/145 (30%)
		IRK_C	213..387	CDD:407551	65/164 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162798
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3449
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D289862at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11767
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.900