Protein Alignment Irk3 and irk-1

DIOPT Version :10

• Sequence 1: NP_001137835.2
• Gene: Irk3 / 35131
• FlyBaseID: FBgn0032706
• Length: 446
• Species: Drosophila melanogaster
• Sequence 2: NP_509138.2
• Gene: irk-1 / 180944
• WormBaseID: WBGene00002149
• Length: 544
• Species: Caenorhabditis elegans
• Alignment Length: 351
• Identity: 126/351 - (35%)
• Similarity: 197/351 - (56%)
• Gaps: 17/351 - (4%)

  Fly    92 TIELTPDLGSGP-RTSSSDGLRRSLNRVMEKNGKENVVFRRIPEKSWRYMRDLVTTLMELEWKYM 155
            |:..|....|.| ...|:..|::|  |::.|||..||....:|:|..:|:||:.||:::::|::|
 Worm    50 TLAFTARRNSSPLYRKSTKKLKKS--RLVGKNGICNVYNTNVPKKDRQYLRDIFTTMIDVKWRWM 112

  Fly   156 LTLFLGSYFLSWLLFAALCYVVAYSHGDF-IFDPVSGKRMGEGVDPCIYGVHSWVAMIIYSVETQ 219
            |.||..::.|||.:|....|::|..|||. :..||:.       ..|:..:.|..:..:::|||.
 Worm   113 LMLFASAFVLSWSIFGTTYYLIALVHGDLSLPTPVNH-------TACVMNLDSVYSSFLFAVETH 170

  Fly   220 TTLGFGEKYASEECPETIFLFVMQMLSAALIEGCMVSVIYAKTARPARQLTKLKFSDKAVICYRD 284
            .|:|:|.:|.:.||.....:..:|.:.|.|::..||.:::||.|||.::...:.||||||||.||
 Worm   171 HTIGYGHRYITTECYLAGAIVCLQAICALLLQSFMVGIVFAKMARPKKRAETIIFSDKAVICLRD 235

  Fly   285 GRLCLLFRVCDPREQQSIESKIRVYIIVDKRTREGETIKSH-VELK----LEGNGEQIILWPDVV 344
            |:||.|.||.|.|....:|:.:|:..|.|:.|.|||....| .|:|    :..:....::||..:
 Worm   236 GQLCFLCRVGDMRNTHLVEAHVRLQFITDRETNEGEIEPLHQFEMKVGPSIADDDRLFLVWPTTL 300

  Fly   345 CHVIDETSPLSQFTTAKLFNAAQFELYVSIVGTSPATAQMTEAKTSYLPREIFWGQRFVNIIHYD 409
            |||||..|||..:....|. :||||:.|.:.|...:|....:|||||||.|:.||.||..::.|.
 Worm   301 CHVIDSRSPLYNYNQQTLM-SAQFEIIVLLEGIVESTGMTAQAKTSYLPSEVLWGHRFRKLVTYQ 364

  Fly   410 AQNERYIVDYENFNRTISVDMPMTNP 435
            ..|..|.:||:.|:.|..|..|..:|
 Worm   365 RSNGSYQIDYDLFHSTYPVRTPAMSP 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk3	NP_001137835.2	IRK	119..265	CDD:460023	47/146 (32%)
		IRK_C	272..432	CDD:465439	67/164 (41%)
irk-1	NP_509138.2	IRK	76..216	CDD:460023	47/146 (32%)
		IRK_C	223..386	CDD:465439	67/163 (41%)