Protein Alignment Irk3 and Kcnj15

DIOPT Version :10

• Sequence 1: NP_001137835.2
• Gene: Irk3 / 35131
• FlyBaseID: FBgn0032706
• Length: 446
• Species: Drosophila melanogaster
• Sequence 2: NP_001034146.1
• Gene: Kcnj15 / 16516
• MGIID: 1310000
• Length: 402
• Species: Mus musculus
• Alignment Length: 383
• Identity: 126/383 - (32%)
• Similarity: 205/383 - (53%)
• Gaps: 41/383 - (10%)

  Fly    92 TIELTPDLGSGPRT---------------SSSDGLRRSLNRVMEKNGKENVVFRRIPEKSWRYMR 141
            |::..|||.|||:.               ::..||:....|||.|:|..||...::......|::
Mouse    15 TLQKIPDLQSGPKMDAIHLGMSSAPLVKHTNGVGLKAHRPRVMSKSGHSNVRIDKVDGIYLLYLQ 79

  Fly   142 DLVTTLMELEWKYMLTLFLGSYFLSWLLFAALCYVVAYSHGDFIFDPVSGKRMGEGVD---PCIY 203
            ||.||:::::|:|.||||..::.::|.||..:.|.:|:.|||.        ::||...   |||.
Mouse    80 DLWTTVIDMKWRYKLTLFAATFVMTWFLFGVVYYAIAFIHGDL--------QLGESNSNHTPCIM 136

  Fly   204 GVHSWVAMIIYSVETQTTLGFGEKYASEECPETIFLFVMQMLSAALIEGCMVSVIYAKTARPARQ 268
            .|.|.....::|:|:|||:|:|.:..:||||..|||.|.|::...|||..:.....||.|||.::
Mouse   137 KVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKR 201

  Fly   269 LTKLKFSDKAVICYRDGRLCLLFRVCDPREQQSIESKIRVYIIVDKRTREGE-------TIKSHV 326
            ...:|||..|||..::|:|||:.:|.:.|:...|:.::...::....|:|||       |:|.||
Mouse   202 AETIKFSHCAVISKQNGKLCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHV 266

  Fly   327 ELKLEGNGEQIILWPDVVCHVIDETSPLSQFTTAKLFNAAQFELYVSIVGTSPATAQMTEAKTSY 391
            :...|   ...::.|....||:||||||...|...| ...:|||.|.:..|..:|:.:.:::|||
Mouse   267 DSSSE---SPFLILPMTFYHVLDETSPLRDLTPQNL-KEKEFELVVLLNATVESTSAVCQSRTSY 327

  Fly   392 LPREIFWGQRFVNIIHYDAQNERYIVDYENFNR-TISVDMPMTNPKNDHLKLE--YRK 446
            :|.||:||..||.::.. ::|.:|:.|:..|.: ..|.|.......::..|||  ||:
Mouse   328 IPEEIYWGFEFVPVVSL-SKNGKYVADFSQFEQIRKSPDCTFYCADSEKQKLEEQYRQ 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk3	NP_001137835.2	IRK	119..265	CDD:460023	53/148 (36%)
		IRK_C	272..432	CDD:465439	55/167 (33%)
Kcnj15	NP_001034146.1	IRK	57..198	CDD:460023	53/148 (36%)
		IRK_C	205..376	CDD:465439	55/175 (31%)