Protein Alignment Irk3 and kcnj2

DIOPT Version :9

• Sequence 1: NP_001137835.2
• Gene: Irk3 / 35131
• FlyBaseID: FBgn0032706
• Length: 446
• Species: Drosophila melanogaster
• Sequence 2: XP_004916397.1
• Gene: kcnj2 / 100497641
• XenbaseID: XB-GENE-1012188
• Length: 425
• Species: Xenopus tropicalis
• Alignment Length: 333
• Identity: 112/333 - (33%)
• Similarity: 189/333 - (56%)
• Gaps: 15/333 - (4%)

  Fly   100 GSGPRTSSSDGLRRSLNRVMEKNGKENVVFRRIPEKSWRYMRDLVTTLMELEWKYMLTLFLGSYF 164
            |.|...|.....::..:|.::|:|..||.|..:.||..||:.|:.||.:::.|::||.:|..::.
 Frog    29 GYGNGKSKIHTRQQCRSRFVKKDGHCNVQFINVSEKGQRYLSDIFTTCVDIRWRWMLVIFCLAFI 93

  Fly   165 LSWLLFAALCYVVAYSHGDFIFDPVSGKRMGEGVDPCIYGVHSWVAMIIYSVETQTTLGFGEKYA 229
            ||||.|..:.:::|..|.| :..|.|.|       ||:..|.|:.|..::|:|||||:|:|.:..
 Frog    94 LSWLFFGCVFWLIALLHED-LGAPESHK-------PCVTQVSSFTAAFLFSIETQTTIGYGFRCV 150

  Fly   230 SEECPETIFLFVMQMLSAALIEGCMVSVIYAKTARPARQLTKLKFSDKAVICYRDGRLCLLFRVC 294
            ::|||..:|:.|.|.:...:|:..::..:.||.|:|.::...|.|||.|||..|||:|||::||.
 Frog   151 TDECPIAVFMVVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSDNAVIAMRDGKLCLMWRVG 215

  Fly   295 DPREQQSIESKIRVYIIVDKRTREGETIK-SHVELKL---EGNGEQIILWPDVVCHVIDETSPLS 355
            :.|:...:|:.:|..::..:.|.|||.|. ..:::.:   .|.....::.|..:.|.|:|.|||.
 Frog   216 NLRKSHLVEAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEINEESPLY 280

  Fly   356 QFTTAKLFNAAQFELYVSIVGTSPATAQMTEAKTSYLPREIFWGQRFVNIIHYDAQNERYIVDYE 420
            ..:...|.| :.||:.|.:.|...|||..|:.::|||..||.||.|:..:: ::.:| .|.|||.
 Frog   281 DLSKQDLDN-SDFEIVVILEGMVEATAMTTQCRSSYLASEILWGHRYEPVL-FEERN-YYKVDYS 342

  Fly   421 NFNRTISV 428
            .|::|..|
 Frog   343 RFHKTYEV 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk3	NP_001137835.2	Ion_trans_2	119..432	CDD:304432	108/314 (34%)
kcnj2	XP_004916397.1	IRK_N	1..47	CDD:369890	3/17 (18%)
		IRK	48..186	CDD:366415	50/145 (34%)
		IRK_C	193..366	CDD:375232	57/161 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D289862at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11767
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.110