Protein Alignment Irk3 and kcnj4

DIOPT Version :9

• Sequence 1: NP_001137835.2
• Gene: Irk3 / 35131
• FlyBaseID: FBgn0032706
• Length: 446
• Species: Drosophila melanogaster
• Sequence 2: XP_002934259.1
• Gene: kcnj4 / 100485222
• XenbaseID: XB-GENE-493748
• Length: 442
• Species: Xenopus tropicalis
• Alignment Length: 355
• Identity: 131/355 - (36%)
• Similarity: 201/355 - (56%)
• Gaps: 17/355 - (4%)

  Fly    97 PDLGSGPRTSSS----DGLRRSLNRVMEKNGKENVVFRRIPEKSWRYMRDLVTTLMELEWKYMLT 157
            |.||:....:||    ...|:..||.::|||:.||.|..:..||.|||.|:.||.::..|:|||.
 Frog    22 PSLGANGNWTSSLHHPHSRRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLL 86

  Fly   158 LFLGSYFLSWLLFAALCYVVAYSHGDF--IFDPVSGKRMGEGVDPCIYGVHSWVAMIIYSVETQT 220
            :|..::..|||.||.|.:.:|:.|||.  ....::|.|.|. ..||:..|:|:|...::||||||
 Frog    87 IFSATFLASWLFFAFLFWCIAFLHGDLGTSSGVIAGGRQGP-PKPCLMHVNSFVEAFLFSVETQT 150

  Fly   221 TLGFGEKYASEECPETIFLFVMQMLSAALIEGCMVSVIYAKTARPARQLTKLKFSDKAVICYRDG 285
            |:|:|.:..::|||..|...|.|.:...||:..|:..|.||.|||.::...|.||..|||..|||
 Frog   151 TIGYGFRCVTDECPLAILAVVAQSILGCLIDSFMIGTIMAKMARPKKRAQTLLFSHHAVIALRDG 215

  Fly   286 RLCLLFRVCDPREQQSIESKIRVYIIVDKRTREGETI---KSHVELKLEGNGEQIIL-WPDVVCH 346
            :|||::||.:.|:...:|:.:|..:|....|:|||.:   :..:.:..:...::|.| .|.::.|
 Frog   216 KLCLMWRVGNLRKSHIVEAHVRAQLIRPYVTQEGEYLPVDQRDLNVGYDSGLDRIFLVSPIIIVH 280

  Fly   347 VIDETSPLSQFTTAK-LFNAAQFELYVSIVGTSPATAQMTEAKTSYLPREIFWGQRFVNIIHYDA 410
            .|||.|||  :|..| ......||:.|.:.|...|||..|:|::|||..||.||.||..:: ::.
 Frog   281 EIDEESPL--YTMGKEQLEGEDFEIVVILEGMVEATAMTTQARSSYLASEIRWGHRFEPVV-FEE 342

  Fly   411 QNERYIVDYENFNRTISV-DMPMTNPKNDH 439
            :| .|.|||.:|::|..| ..|:.:.:..|
 Frog   343 KN-HYKVDYSHFHKTYQVPGTPVCSARELH 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk3	NP_001137835.2	Ion_trans_2	119..432	CDD:304432	121/320 (38%)
kcnj4	XP_002934259.1	IRK_N	1..47	CDD:369890	7/24 (29%)
		IRK	48..195	CDD:366415	59/147 (40%)
		IRK_C	202..372	CDD:375232	62/174 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D289862at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11767
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020