Protein Alignment Irk3 and Kcnj13

DIOPT Version :9

• Sequence 1: NP_001137835.2
• Gene: Irk3 / 35131
• FlyBaseID: FBgn0032706
• Length: 446
• Species: Drosophila melanogaster
• Sequence 2: NP_001103697.1
• Gene: Kcnj13 / 100040591
• MGIID: 3781032
• Length: 360
• Species: Mus musculus
• Alignment Length: 333
• Identity: 98/333 - (29%)
• Similarity: 161/333 - (48%)
• Gaps: 43/333 - (12%)

  Fly   102 GPRTSSSDGLRRSLNRVMEKNGKENVVFRRIPEKSWRYMRDLVTTLMELEWKYMLTLFLGSYFLS 166
            |..|...||.:|.|                      .|:||....||::.|::|:.:|..|:.:.
Mouse    25 GHSTLQMDGAQRGL----------------------VYLRDAWGILMDMRWRWMMLVFSASFVVH 67

  Fly   167 WLLFAALCYVVAYSHGDFIFDPVSGKRMGEGVDP-----CIYGVHSWVAMIIYSVETQTTLGFGE 226
            ||:||.|.|.||..:||...|        ..|.|     |:..:.|:.|...:|:|||.|:|:|.
Mouse    68 WLVFAVLWYAVAEMNGDLEID--------HDVPPENHTICVKHITSFTAAFSFSLETQLTIGYGT 124

  Fly   227 KYASEECPETIFLFVMQMLSAALIEGCMVSVIYAKTARPARQLTKLKFSDKAVICYRDGRLCLLF 291
            .:.|.:||..|.|..:|||...::|..:.....||.|||..:...::|:|.||:.::||:..|:|
Mouse   125 MFPSGDCPSAIALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDLAVVAHKDGKPNLIF 189

  Fly   292 RVCDPREQQSIESKIRVYIIVDKRTREGETIKSHVELKLEGNGEQ---IILWPDVVCHVIDETSP 353
            :|.:.|  .|..:.:||..::.:....||..::.|:..|:|...:   ..::|....|.|..:||
Mouse   190 QVANTR--PSPLTNVRVSAVLYQERENGELYQTSVDFHLDGISSEECPFFIFPLTYYHTISPSSP 252

  Fly   354 LSQFTTAKLFNAAQFELYVSIVGTSPATAQMTEAKTSYLPREIFWGQRFVNIIHYDAQNERYIVD 418
            |:  |..:......|||.|.:......|.::.:.:|||||.||....||..::...::.| |.|.
Mouse   253 LA--TLLQHETPPHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHRFAALMTRGSKGE-YQVK 314

  Fly   419 YENFNRTI 426
            .|||::|:
Mouse   315 MENFDKTV 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irk3	NP_001137835.2	Ion_trans_2	119..432	CDD:304432	92/316 (29%)
Kcnj13	NP_001103697.1	IRK	21..163	CDD:395797	50/167 (30%)
		Selectivity filter. /evidence=ECO:0000250|UniProtKB:O60928	119..124		2/4 (50%)
		IRK_C	170..331	CDD:407551	46/158 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843283
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11767
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.030