DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Faf2 and AT4G10790

DIOPT Version :9

Sequence 1:	NP_001286057.1	Gene:	Faf2 / 35129	FlyBaseID:	FBgn0025608	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	NP_192817.1	Gene:	AT4G10790 / 826675	AraportID:	AT4G10790	Length:	480	Species:	Arabidopsis thaliana

Alignment Length:	523	Identity:	133/523 - (25%)
Similarity:	222/523 - (42%)	Gaps:	120/523 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 EQTEKVLQFQDLTGIEDMNVCRDVLIRHQWDLEVAFQEQLNIREGRPTMFAASTDVRAPAVLNDR 73
            :..:|:..||.:||:||.::|.::|..|.||||:|.           :.|.:|.
plant     3 DTVDKLGYFQAITGLEDADLCTEILQAHGWDLELAI-----------SSFTSSD----------- 45

  Fly    74 FLQQVFSANMPGG--------RTVSRVPSGPVPRSFT-----------------GIIGYVINFVF 113
              |...|:.:.||        ...:..|..| ||...                 |:...:|....
plant    46 --QDASSSAVDGGGNNRDHDHNNATVTPDYP-PRGIVDDTELVMRDDGGGNRGPGVAWRIITLPI 107

  Fly   114 QYFYSTLTSIVSAFVNL----------------------GGGNE-ARL--VTDPLGDVMKFIREY 153
            .....:| .:||..:.|                      |||:| |||  |:..:|:.|:|:..:
plant   108 SIVSGSL-GLVSGAIGLGIWAAGGVLSYSLGMLGFRSGRGGGSESARLVSVSSAVGEAMEFVALF 171

  Fly   154 YERYPEHPVF-----YQGTYAQALNDAKQELRFLIVYLHKDPAKNPDVESFCRNTLSARSVIDYI 213
            ...|..:..|     .:| :..||..::...:.|.||||.  ..:||...||..||...:|:.::
plant   172 DRDYGSNNAFKIDFVVEG-FMDALQRSRSSFKLLFVYLHS--PDHPDTPVFCGGTLCNEAVVAFV 233

  Fly   214 NTHTLLWGCDVATPEGYRVMQSITVRSYPTMVMISLRAN-RMMIVGRFEGDCTPEELLRRLQSVT 277
            |.:.:.||..:.:.||:::..|:....:|...::...|| |:.::.:.||..:|||:|..||.:.
plant   234 NENFVSWGGSIRSSEGFKMSNSLKASRFPFCAVVMPAANQRIALLQQVEGPKSPEEMLAILQRIV 298

  Fly   278 NANEVWLSQARADRLERNFTQTLRRQQDEAYEQSLLADEEKERQRQRERD-----------AVRQ 331
            ..:...|..||.:..||.....||.:||.||..:|.||:.:|:|||.|::           .:::
plant   299 EDSSPTLVTARVEAEERRTNLRLREEQDAAYRAALEADQAREQQRQEEKERLEREAAEAERKLKE 363

  Fly   332 AEEAVEQARRDVELRKEEIARQKIELATLVPSEPAADAVGAIAVVFKLPSGTRLERRFNQTDSVL 396
            .|||.|:|.|:.|.|:....|.:.|.|..:..|| ........|:.:.|:|.|..|.|.....:.
plant   364 EEEARERAAREAEERQAARVRMRQEKALALGEEP-EKGPDVTQVLVRFPNGERKGRMFKSETKIQ 427

  Fly   397 DVYHYLFCHPDS-----PDEFEITTNFPKRVLFSKANLDAAGETGTAKETLTKTLQAVGLKNREV 456
            .:|.|:    ||     .:|:.:.||||:.|.            |..||::  :|:..||..:..
plant   428 TLYDYV----DSLGLLDTEEYSLITNFPRTVY------------GRDKESM--SLKDAGLHPQAS 474

  Fly   457 LFV 459
            ||:
plant   475 LFI 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Faf2	NP_001286057.1	UBA_FAF2	12..49	CDD:270597	15/36 (42%)
		UAS_ETEA	163..280	CDD:239289	34/122 (28%)
		ATP-synt_B	<287..>373	CDD:304375	31/96 (32%)
		UBQ	373..462	CDD:294102	24/92 (26%)
AT4G10790	NP_192817.1	UBA_FAF	11..42	CDD:270538	14/41 (34%)
		UAS	173..295	CDD:214737	33/124 (27%)
		tolA_full	237..>362	CDD:274303	36/124 (29%)
		SPFH_like	<317..360	CDD:302763	14/42 (33%)
		UBX	398..478	CDD:279169	24/98 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	116	1.000	Domainoid score	I1962
eggNOG	1	0.900	-	-		E1_KOG1363
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8753
Inparanoid	1	1.050	146	1.000	Inparanoid score	I1752
OMA	1	1.010	-	-		QHG53584
OrthoDB	1	1.010	-	-		D1251507at2759
OrthoFinder	1	1.000	-	-		FOG0005640
OrthoInspector	1	1.000	-	-		oto4274
orthoMCL	1	0.900	-	-		OOG6_102329
Panther	1	1.100	-	-	O	PTHR23322
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X5289
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840