DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Faf2 and UBXN8

DIOPT Version :9

Sequence 1:	NP_001286057.1	Gene:	Faf2 / 35129	FlyBaseID:	FBgn0025608	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	XP_011542957.1	Gene:	UBXN8 / 7993	HGNCID:	30307	Length:	327	Species:	Homo sapiens

Alignment Length:	239	Identity:	50/239 - (20%)
Similarity:	96/239 - (40%)	Gaps:	62/239 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   269 LLRRLQSVTNANEVWLSQARADRL------ERN--FTQTLRRQQDEA-------YEQSLLADEEK 318
            ||....|||.:   ||:..::.::      |:|  ..:.:|::|.||       |.:::|...::
Human   104 LLTLTISVTTS---WLNSFKSPQVYLKEEEEKNEKRQKLVRKKQQEAQGEKASRYIENVLKPHQE 165

  Fly   319 ERQRQRERDAVRQAEEAVE------------QARRDVELRKEEIARQK------------IELAT 359
            .:.|:.|....:...||.:            .::...|....|.|:.:            .|..|
Human   166 MKLRKLEERFYQMTGEAWKLSSGHKLGGDEGTSQTSFETSNREAAKSQNLPKPLTEFPSPAEQPT 230

  Fly   360 L-----VPSEPAADAVGAIAVVFKLPSGTRLERRFNQTDSVLDVYHYLFCHPDSPDEFEITTNFP 419
            .     :|.||:..|...:.|..:.|||..|.|||.::.|...::.::.........:.::|:||
Human   231 CKEIPDLPEEPSQTAEEVVTVALRCPSGNVLRRRFLKSYSSQVLFDWMTRIGYHISLYSLSTSFP 295

  Fly   420 KRVLFSKANLDAAGETGTAKETLTKTLQAVGLKNREVLFVNDLE 463
            :|.|        |.|.|       ::|:.:|:....||.:.:.|
Human   296 RRPL--------AVEGG-------QSLEDIGITVDTVLILEEKE 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Faf2	NP_001286057.1	UBA_FAF2	12..49	CDD:270597
		UAS_ETEA	163..280	CDD:239289	5/10 (50%)
		ATP-synt_B	<287..>373	CDD:304375	21/129 (16%)
		UBQ	373..462	CDD:294102	21/88 (24%)
UBXN8	XP_011542957.1	UBX	243..322	CDD:279169	22/93 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141665
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1363
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23322
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.930