DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Faf2 and ubxn8

DIOPT Version :9

Sequence 1:	NP_001286057.1	Gene:	Faf2 / 35129	FlyBaseID:	FBgn0025608	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	NP_001019583.1	Gene:	ubxn8 / 554116	ZFINID:	ZDB-GENE-050522-266	Length:	272	Species:	Danio rerio

Alignment Length:	235	Identity:	44/235 - (18%)
Similarity:	92/235 - (39%)	Gaps:	50/235 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   254 MMIVGR---FEGDCT-PEELLRRL--------QSVTNANEVWLSQARADRLERNFTQTLRRQQDE 306
            :.:.||   |.|.|| ...:..||        |.:|::.....|:.:.:::.|. .|.|:..:..
Zfish    31 LKLAGRGFIFLGICTWLISIFPRLKFFFFPVTQELTDSPTPESSRLKEEQVRRT-QQDLQNDKMS 94

  Fly   307 AYEQSLLADEEKERQRQR----------------------ERDAVRQAEEAVEQARRDVELRK-- 347
            .|.:::|...:....:|:                      :.|.:..|.:..|...:....|:
Zfish    95 DYAENVLKPRQNSLLQQKTERYYRMTGETWKLSPGLPVGGDEDKICHAVDVDESPNQGARRRRKP 159

  Fly   348 ----------EEIARQKIELATLVPSEPAADAVGAIAVVFKLPSGTRLERRFNQTDSVLDVYHYL 402
                      ||:.:||  ...::|.||:.|..||:.:..:.|....:.|||.:|.|...:..::
Zfish   160 MQTVTQDPVQEEVPKQK--RVIVLPDEPSVDTEGAVKIALRFPGRRAIHRRFLKTWSSQLLLEWM 222

  Fly   403 FCHPDSPDEFEITTNFPKRVLFSKANLDAAGETGTAKETL 442
            ......|..:.:..::|:..:.:.|:: :..|.|...:||
Zfish   223 MKTGYPPALYTLYMSYPRTEVQTAADM-SLEEAGIHTDTL 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Faf2	NP_001286057.1	UBA_FAF2	12..49	CDD:270597
		UAS_ETEA	163..280	CDD:239289	10/37 (27%)
		ATP-synt_B	<287..>373	CDD:304375	19/119 (16%)
		UBQ	373..462	CDD:294102	13/70 (19%)
ubxn8	NP_001019583.1	UBQ	190..266	CDD:294102	15/73 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574670
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840