DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Faf2 and Ubxn8

DIOPT Version :9

Sequence 1:	NP_001286057.1	Gene:	Faf2 / 35129	FlyBaseID:	FBgn0025608	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	NP_001099556.1	Gene:	Ubxn8 / 290802	RGDID:	1306023	Length:	276	Species:	Rattus norvegicus

Alignment Length:	237	Identity:	54/237 - (22%)
Similarity:	88/237 - (37%)	Gaps:	65/237 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   251 ANRMMIVGRFEGDCTPEELLRRLQSVTNANEVWLSQARADRLERNFTQTL----------RRQQD 305
            |.|..:....:.:...|:..|.:|:|....:    :.:..:||..|.|..          |.::|
  Rat    77 AKRQKLARERQQEAQGEKASRYIQNVLKPQQ----EMKLKKLEERFYQMTGETWKLSTGHRLEED 137

  Fly   306 EAYEQSLLADEEKERQRQRERDAVRQAEEAVEQARRD------VELRKEEIARQKIELATLVPSE 364
            |        |.|.|...|...:.|..     |.|||.      .|:........:.|:..| |.|
  Rat   138 E--------DSEFENSSQASFETVNG-----EAARRQNLPKFLTEISPPAQPPSRKEVPDL-PEE 188

  Fly   365 PAADAVGAIAVVFKLPSGTRLERRFNQT-------DSVLDV-YHYLFCHPDSPDEFEITTNFPKR 421
            |:..|.|.:.|..:.|||..|.|||.::       |.::.: ||...        :.::|:||:|
  Rat   189 PSETAEGVVTVALRCPSGHLLRRRFFKSWNSQVLFDWMMKIGYHRSL--------YGLSTSFPRR 245

  Fly   422 VLFSKANLDAAGETGTAKETLTKTLQAVGLKNREVLFVNDLE 463
            .|          |.|..     .:|:.:|:....||.|.:.|
  Rat   246 PL----------EVGGG-----SSLEDIGITVDTVLNVEERE 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Faf2	NP_001286057.1	UBA_FAF2	12..49	CDD:270597
		UAS_ETEA	163..280	CDD:239289	6/28 (21%)
		ATP-synt_B	<287..>373	CDD:304375	24/101 (24%)
		UBQ	373..462	CDD:294102	23/96 (24%)
Ubxn8	NP_001099556.1	UBQ	191..270	CDD:294102	25/101 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335356
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1363
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23322
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.930