DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Faf2 and Faf1

DIOPT Version :9

Sequence 1:	NP_001286057.1	Gene:	Faf2 / 35129	FlyBaseID:	FBgn0025608	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	NP_569090.2	Gene:	Faf1 / 140657	RGDID:	70987	Length:	649	Species:	Rattus norvegicus

Alignment Length:	349	Identity:	95/349 - (27%)
Similarity:	168/349 - (48%)	Gaps:	58/349 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   144 GD-VMKFIREYYERYPE-HPVFYQGTYAQALNDA----KQELRFLIVYLHKDPAKNPDVESFCRN 202
            || :::|..|:..||.: ||||:.|:...|..:|    .::.:.|.:|||.|.:...:|  ||..
  Rat   330 GDALLQFTAEFSSRYGDCHPVFFIGSLEAAFQEAFYVKARDRKLLAIYLHHDESVLTNV--FCSQ 392

  Fly   203 TLSARSVIDYINTHTLLWGCDVATPEGYRVMQSITVRSYPTMVMISLRANR-------MMIVGR- 259
            .|.|.|::.|::.:.:.|..|:..........::..|.:.:::..::|..:       ::|:|:
  Rat   393 MLCAESIVSYLSQNFITWAWDLTKDANRARFLTMCNRHFGSVIAQTIRTQKTDQFPLFLIIMGKR 457

  Fly   260 --------FEGDCTPEELLRRLQSVTNANEVWLSQAR---ADRLERNFTQTLRRQQDEAYEQSLL 313
                    .:|:.|.:||:.||.:   |.|::.:|.:   .|..||...:.::|:|||||..||.
  Rat   458 SSNEVLNVIQGNTTVDELMMRLMA---AMEIFSAQQQEDIKDEDEREARENVKREQDEAYRLSLE 519

  Fly   314 ADEEKERQRQRERDAVRQAEE-AVEQARRDVELRKEEIARQKIELATLVPSEPA---ADAVGAIA 374
            ||..|....:||     .||: .:||.|::.|..:|.|   ::.|...:|.||.   |:.|..:.
  Rat   520 ADRAKREAHERE-----MAEQFRLEQIRKEQEEEREAI---RLSLEQALPPEPEEENAEPVSKLR 576

  Fly   375 VVFKLPSGTRLERRFNQTDSVLDVYHYLFCHPDSPDEFEITTNFPKRVLFSKANLDAAGETGTAK 439
            :  :.|||..|||||..::.:..|:.::.......|||::.:.||:|   ....||.
  Rat   577 I--RTPSGEFLERRFLASNKLQIVFDFVASKGFPWDEFKLLSTFPRR---DVTQLDP-------- 628

  Fly   440 ETLTKTLQAVGLKNREVLFVNDLE 463
               .|:|..|.|..:|.||:...|
  Rat   629 ---NKSLLEVNLFPQETLFLQAKE 649

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Faf2	NP_001286057.1	UBA_FAF2	12..49	CDD:270597
		UAS_ETEA	163..280	CDD:239289	28/136 (21%)
		ATP-synt_B	<287..>373	CDD:304375	30/92 (33%)
		UBQ	373..462	CDD:294102	24/88 (27%)
Faf1	NP_569090.2	UBA_FAF1	14..46	CDD:270596
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	55..84
		Ubl1_FAF1	99..171	CDD:340649
		Ubl_FAF1	194..267	CDD:340576
		UAS_FAF1	351..486	CDD:239288	30/139 (22%)
		DUF5401	<460..>558	CDD:375164	34/108 (31%)
		UBX_UBXN3A	572..648	CDD:340469	25/91 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1363
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810