DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jwa and praf2

DIOPT Version :9

Sequence 1:	NP_609901.5	Gene:	Jwa / 35128	FlyBaseID:	FBgn0032704	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_001017698.1	Gene:	praf2 / 550393	ZFINID:	ZDB-GENE-050417-190	Length:	178	Species:	Danio rerio

Alignment Length:	195	Identity:	73/195 - (37%)
Similarity:	107/195 - (54%)	Gaps:	31/195 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 NLQLPPLRTLDDFILGSARFQLPNLKDFEKWGNRVVKNLLYYQTNYFLLFITIYVLMIFFNPSKI 124
            :.|.|||||||||:|.||||.||::::.::|.||::.||||||.|||.......|::.:|...|:
Zfish     3 DFQPPPLRTLDDFLLSSARFSLPDVRNLDRWNNRIINNLLYYQLNYFATASAFLVIVGYFQTLKL 67

  Fly   125 ITGLLVQALI-IGVIWQFFSGKSKKNFIASRLTGGNANAAEQNAQQKWY------ILAGALLG-G 181
            |.|..|..:: :|.:|                      |||..|..:.:      :...|:|| .
Zfish    68 ILGAAVVIIVFLGFVW----------------------AAENKAVIRRFRRNHPSLSLAAILGSS 110

  Fly   182 YLLLHLLSAVLLTIFTVLLPISLTFIHASLRLRNIKNKLTNSIESFA-PSTPMGSLLDALNVRAE 245
            ||.|.:|..|.:.:|.:..||.:..:|||:|||::||||.|.:||.. ..||||.:|:||....|
Zfish   111 YLFLSVLGGVAVFLFGIAFPILMILVHASVRLRSLKNKLENKLESIGLKRTPMGLVLEALGQEQE 175

Fly 246 245
Zfish 176 175

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jwa	NP_609901.5	PRA1	62..220	CDD:281235	60/165 (36%)
praf2	NP_001017698.1	PRA1	5..149	CDD:281235	60/165 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583563
Domainoid	1	1.000	108	1.000	Domainoid score	I6370
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	125	1.000	Inparanoid score	I4680
OMA	1	1.010	-	-		QHG49062
OrthoDB	1	1.010	-	-		D1288023at2759
OrthoFinder	1	1.000	-	-		FOG0003654
OrthoInspector	1	1.000	-	-		otm25919
orthoMCL	1	0.900	-	-		OOG6_105959
Panther	1	1.100	-	-	LDO	PTHR12859
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3380
SonicParanoid	1	1.000	-	-		X2527
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.940