DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jwa and praf-3

DIOPT Version :9

Sequence 1:	NP_609901.5	Gene:	Jwa / 35128	FlyBaseID:	FBgn0032704	Length:	249	Species:	Drosophila melanogaster
Sequence 2:	NP_001023104.1	Gene:	praf-3 / 177637	WormBaseID:	WBGene00017070	Length:	186	Species:	Caenorhabditis elegans

Alignment Length:	204	Identity:	66/204 - (32%)
Similarity:	103/204 - (50%)	Gaps:	22/204 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 MTTPSTSVGDAAAALSGNLQLPPLRTLDDFILGSARFQLPNLKDFEKWGNRVVKNLLYYQTNYFL 107
            |||.|.::     .:...:::||.|...:|:|.:.|::.|...||:||.||::.||||:|||||:
Worm     1 MTTSSENM-----QIMNGVEVPPFRNFHEFLLETDRYERPPFNDFKKWNNRIISNLLYFQTNYFV 60

  Fly   108 LFITIYVLMIFFNPSKIITGLLVQALIIGVIWQFFSGKSKKNFIASRLTGGNANAAEQNAQQKWY 172
            ..||:::|..|.:...|..||:....:|..:  .|:            ...:||..:........
Worm    61 TIITLFLLHTFISSQDIFVGLIAVVAVIATL--IFA------------VSADANIKKMRTDHPLV 111

  Fly   173 ILAGALLGGYLLLHLLSAVLLTIFTVLLPISLTFIHASLRLRNIKNKLTNSIESFAPSTP-MGSL 236
            .|.|.:|..|..:.:..:||:..|.:|.|:.|..:|||||||.|.|:..|..|.....|. ||.:
Worm   112 TLGGIILVAYFFISVFQSVLVVAFALLFPVFLVLVHASLRLRGIANRAANVKEQLGIRTSVMGQI 176

  Fly   237 LD--ALNVR 243
            ||  .|||:
Worm   177 LDRTGLNVK 185

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jwa	NP_609901.5	PRA1	62..220	CDD:281235	52/157 (33%)
praf-3	NP_001023104.1	PRA1	15..158	CDD:281235	51/156 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160160743
Domainoid	1	1.000	106	1.000	Domainoid score	I4112
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4673
Inparanoid	1	1.050	115	1.000	Inparanoid score	I3396
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49062
OrthoDB	1	1.010	-	-		D1288023at2759
OrthoFinder	1	1.000	-	-		FOG0003654
OrthoInspector	1	1.000	-	-		oto19871
orthoMCL	1	0.900	-	-		OOG6_105959
Panther	1	1.100	-	-	LDO	PTHR12859
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3380
SonicParanoid	1	1.000	-	-		X2527
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.940