Protein Alignment CG10376 and PPM1H

DIOPT Version :9

• Sequence 1: NP_609899.1
• Gene: CG10376 / 35126
• FlyBaseID: FBgn0032702
• Length: 428
• Species: Drosophila melanogaster
• Sequence 2: NP_065751.1
• Gene: PPM1H / 57460
• HGNCID: 18583
• Length: 514
• Species: Homo sapiens
• Alignment Length: 423
• Identity: 81/423 - (19%)
• Similarity: 140/423 - (33%)
• Gaps: 155/423 - (36%)

  Fly   143 DEAAPENCECHQQKEPLHTSAAVKNKP-RKMEDRCVCLDRFGEMYELLDK------TTRFFGVFD 200
            |:|   :||....|:   .:.||.:.| |....|...|.. ||..:|.:.      :..::.:||
Human    94 DQA---SCEVLTVKK---KAGAVTSTPNRNSSKRRSSLPN-GEGLQLKENSESEGVSCHYWSLFD 151

  Fly   201 GHSGSLSATYATSQLPQLLADQLK----------------------------------------- 224
            ||:||.:|..|:..|...:.:||:
Human   152 GHAGSGAAVVASRLLQHHITEQLQDIVDILKNSAVLPPTCLGEEPENTPANSRTLTRAASLRGGV 216

  Fly   225 -ANPDPAAFSPDFYR-----------NAFESAFLLADERFTQKK----ITSGTTSVCALITKDQL 273
             |...|:.....|:.           .|.||||...|.:..:::    |:.|.|::..:....:|
Human   217 GAPGSPSTPPTRFFTEKKIPHECLVIGALESAFKEMDLQIERERSSYNISGGCTALIVICLLGKL 281

  Fly   274 YIAWVGDSKALLVGKRTQLQLVKPHKPENPDERKRIETAGGTVLHAQGQ---------------- 322
            |:|..|||:|:::.....:.:.....||.  ||:|::.......|..|.
Human   282 YVANAGDSRAIIIRNGEIIPMSSEFTPET--ERQRLQYLAFMQPHLLGNEFTHLEFPRRVQRKEL 344

  Fly   323 -------------W----------------------RVNGILNVARSIGDYSLEA---------- 342
                         |                      ||...:.|.|.:||:.|:.
Human   345 GKKMLYRDFNMTGWAYKTIEDEDLKFPLIYGEGKKARVMATIGVTRGLGDHDLKVHDSNIYIKPF 409

  Fly   343 VIAEPDFVDVQLNE----AHDFLVLGTDGLWDHVPESLIIETVYDSLADT--------TMKLDDI 395
            :.:.|:.....|::    :.|.|:|.||||||.:....:.|.:...|.:.        |:...|:
Human   410 LSSAPEVRIYDLSKYDHGSDDVLILATDGLWDVLSNEEVAEAITQFLPNCDPDDPHRYTLAAQDL 474

  Fly   396 PKLLIEAAKER---------DSQDNITAVVVLL 419
            ........|:|         .|.|:|:..|:.|
Human   475 VMRARGVLKDRGWRISNDRLGSGDDISVYVIPL 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10376	NP_609899.1	PP2Cc	160..419	CDD:238083	75/404 (19%)
PPM1H	NP_065751.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	109..135		9/26 (35%)
		PP2Cc	143..507	CDD:238083	66/365 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144718
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840