Protein Alignment CG10376 and PPM1G

DIOPT Version :9

• Sequence 1: NP_609899.1
• Gene: CG10376 / 35126
• FlyBaseID: FBgn0032702
• Length: 428
• Species: Drosophila melanogaster
• Sequence 2: NP_817092.1
• Gene: PPM1G / 5496
• HGNCID: 9278
• Length: 546
• Species: Homo sapiens
• Alignment Length: 515
• Identity: 114/515 - (22%)
• Similarity: 185/515 - (35%)
• Gaps: 164/515 - (31%)

  Fly    44 TANETYKVSGEERH---AELVSAIWKQLETRGCPAQFRIKLLHRSTQQLEQDLCFAKECEVTVEG 105
            :|.:.::||.|:.|   .||.|      ||    |.|.:...|...   |..|..||.....::.
Human    30 SAMQGWRVSMEDAHNCIPELDS------ET----AMFSVYDGHGGE---EVALYCAKYLPDIIKD 81

  Fly   106 PPQYDLLKLQKFVASEFEKYILKLTDNSEV--------------DRLKDFADEAAPENCE----- 151
            ...|...||||.:...|.....|||....:              |..:..|||...:|.|
Human    82 QKAYKEGKLQKALEDAFLAIDAKLTTEEVIKELAQIAGRPTEDEDEKEKVADEDDVDNEEAALLH 146

  Fly   152 -----------------CHQQKEPLHTSA---------------------------AVKNKP--- 169
                             ||  |.|.|:.:                           :.:|.|
Human   147 EEATMTIEELLTRYGQNCH--KGPPHSKSGGGTGEEPGSQGLNGEAGPEDSTRETPSQENGPTAK 209

  Fly   170 -----RKMEDRCVCLDRFGEMYELLDKTTRFFGVFDGHSGSLSATYATSQLPQLL---------- 219
                 ....:|.....:.||.           |:..|.:|. |.:.|:.:||::.
Human   210 AYTGFSSNSERGTEAGQVGEP-----------GIPTGEAGP-SCSSASDKLPRVAKSKFFEDSED 262

  Fly   220 ----ADQLKANPDPAAFSPDFYRNAFESAFLLADERFTQKK-----------------------I 257
                |::.:.:.:..:...|.|.:  |.|....||..|::.                       .
Human   263 ESDEAEEEEEDSEECSEEEDGYSS--EEAENEEDEDDTEEAEEDDEEEEEEMMVPGMEGKEEPGS 325

  Fly   258 TSGTTSVCALITKDQLYIAWVGDSKALLVGKRTQLQLVKPHKPENPDERKRIETAGGTVLHAQGQ 322
            .||||:|.|||...||.:|..|||:.::......|.:...||||:..|..||:.|||.|..   .
Human   326 DSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGKVTM---D 387

  Fly   323 WRVNGILNVARSIGDY----------SLEAVIAEPDFVDVQLNEAHDFLVLGTDGLWDHVPESLI 377
            .||||.||::|:|||:          ..:.:.|.||...:.|.:.|:|:|:..||:|:.:....:
Human   388 GRVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPDIKVLTLTDDHEFMVIACDGIWNVMSSQEV 452

  Fly   378 IETVYDSLADTTMK-----LDDIPKLLIEAAKERDSQ------DNITAVVVLLKPRHQIE 426
            ::.:...::.....     |..|.:.|::.....|:.      ||:|.:::..|||:..|
Human   453 VDFIQSKISQRDENGELRLLSSIVEELLDQCLAPDTSGDGTGCDNMTCIIICFKPRNTAE 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10376	NP_609899.1	PP2Cc	160..419	CDD:238083	74/351 (21%)
PPM1G	NP_817092.1	PP2Cc	25..>110	CDD:214625	26/92 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	116..139		4/22 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	161..328		25/182 (14%)
		PP2Cc	<324..505	CDD:238083	53/183 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	512..546		1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0631
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810