DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10376 and Ppm1e

DIOPT Version :9

Sequence 1:	NP_609899.1	Gene:	CG10376 / 35126	FlyBaseID:	FBgn0032702	Length:	428	Species:	Drosophila melanogaster
Sequence 2:	NP_942068.1	Gene:	Ppm1e / 360593	RGDID:	735028	Length:	750	Species:	Rattus norvegicus

Alignment Length:	382	Identity:	131/382 - (34%)
Similarity:	195/382 - (51%)	Gaps:	37/382 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 KVSGEERHAELVSAIWKQLETRGCPAQFRIKLLHRST--QQLEQDL---CFAKECEVTVEGPPQY 109
            :::.||...|.:....:||....||: |....|.|:|  :.|:.||   |..||.:.| ||..:.
  Rat   131 RITREEVEGESLDLCLQQLYKYNCPS-FLAAALARATSDEVLQSDLSAHCIPKETDGT-EGTVEI 193

  Fly   110 DLLKLQKFVASEFEKYILKLTDNSEVDRLKDFADEAAPENCECHQQKEPLHTSAAVKNKPRKMED 174
            :.:||.:.|.|:..:..        .:.:|||.....|:    ...:..:|   |:||..|||||
  Rat   194 ETVKLARSVFSKLHEIC--------CNWVKDFPLRRRPQ----IYYETSIH---AIKNMRRKMED 243

  Fly   175 RCVCLDRFGEMYELLDKTTR-FFGVFDGHSGSLSATYATSQLPQLLADQLKANPDPAAFSPDFYR 238
            :.||:..|..::.|.|:..: :|.|||||.|..:|.||:..|...|..|.....|||
  Rat   244 KHVCIPDFNMLFNLEDQEEQAYFAVFDGHGGVDAAIYASVHLHVNLVRQEMFPHDPA-------- 300

  Fly   239 NAFESAFLLADERFTQK----KITSGTTSVCALITKDQLYIAWVGDSKALLVGKRTQLQLVKPHK 299
            .|...||.:.||||.||    .:..|||.|...|..:.|::||||||:.:||.|...::|:||||
  Rat   301 EALCRAFRVTDERFVQKAARESLRCGTTGVVTFIRGNMLHVAWVGDSQVMLVRKGQAVELMKPHK 365

  Fly   300 PENPDERKRIETAGGTVLHAQGQWRVNGILNVARSIGDYSLEAVI-AEPDFVDVQLNEAHDFLVL 363
            |:..||::|||..||.|:.. |.|||||.|:|:|:|||...:..| .:.|.....|:...|:|:|
  Rat   366 PDREDEKQRIEALGGCVVWF-GAWRVNGSLSVSRAIGDAEHKPYICGDADSASTVLDGTEDYLIL 429

  Fly   364 GTDGLWDHVPESLIIETVYDSLADTTMKLDDIPKLLIEAAKERDSQDNITAVVVLLK 420
            ..||.:|.|.....::.|.|.|.:.......:...|:.:|::..|.||||.:||.|:
  Rat   430 ACDGFYDTVNPDEAVKVVSDHLKENNGDSSMVAHKLVASARDAGSSDNITVIVVFLR 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10376	NP_609899.1	PP2Cc	160..419	CDD:238083	102/264 (39%)
Ppm1e	NP_942068.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	21..128
		7 X 2 AA tandem repeats of P-E	31..44
		PP2Cc	227..485	CDD:238083	102/269 (38%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	495..535
		M-inducer_phosp	<505..>554	CDD:284119
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338425
Domainoid	1	1.000	156	1.000	Domainoid score	I4096
eggNOG	1	0.900	-	-		E1_COG0631
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1044139at2759
OrthoFinder	1	1.000	-	-		FOG0002007
OrthoInspector	1	1.000	-	-		otm45746
orthoMCL	1	0.900	-	-		OOG6_106247
Panther	1	1.100	-	-	O	PTHR13832
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X119
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.710