DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10376 and Ppm1g

DIOPT Version :9

Sequence 1:	NP_609899.1	Gene:	CG10376 / 35126	FlyBaseID:	FBgn0032702	Length:	428	Species:	Drosophila melanogaster
Sequence 2:	NP_671742.1	Gene:	Ppm1g / 259229	RGDID:	628676	Length:	542	Species:	Rattus norvegicus

Alignment Length:	504	Identity:	111/504 - (22%)
Similarity:	190/504 - (37%)	Gaps:	150/504 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 SRSCVTRTANETYKVSGEERHAELVSAIW--KQLETRGCPAQFRIKLLHR--STQQLEQDLCFAK 97
            :.:|:....|||...|..:.|.....|::  |.|     |...:.:..::  ..|:..||...|.
  Rat    42 AHNCIPELDNETAMFSVYDGHGGEEVALYCAKYL-----PDIIKDQKAYKEGKLQKALQDAFLAI 101

  Fly    98 ECEVTVEGPPQYDLLKLQKFVA---SEFEKYILKLTDNSEVDRLKDFADEAA------------- 146
            :.::|.:     :::|....:|   :|.|....|:.|..:||.     :|||
  Rat   102 DAKLTTD-----EVIKELAQIAGRPTEDEDDKEKVADEDDVDN-----EEAALLHEEATMTIEEL 156

  Fly   147 ----PENCECHQQKEPLHT-----------------------------------SAAVKNKPRKM 172
                .:||    ||.|.||                                   :|.....|...
  Rat   157 LTRYGQNC----QKGPPHTKSGTGIGDEPEPQGLNGEAGPEDPSRETPSQENGPTAKGHTGPSSN 217

  Fly   173 EDRCVCLDRFGEMYELLDKTTRFFGVFDGHSGSLSATYATSQLPQLL-----------ADQLKAN 226
            .|......:.||.           |...|.:|. |.:.|:.:||::.           :|:::..
  Rat   218 SDHGTEAGQIGEP-----------GTATGEAGP-SCSSASDKLPRVAKSKFFEDSEDESDEVEEE 270

  Fly   227 PDPA---AFSPDFYRNAFESAFLLADERFTQKK--------------------ITSGTTSVCALI 268
            .|.:   :...|.|.:  |.|....||..|::.                    ..||||:|.|||
  Rat   271 EDDSEECSEDEDGYSS--EEAENEEDEDDTEEAEEDDDEEMMVPGMEGKEEPGSDSGTTAVVALI 333

  Fly   269 TKDQLYIAWVGDSKALLVGKRTQLQLVKPHKPENPDERKRIETAGGTVLHAQGQWRVNGILNVAR 333
            ...||.:|..|||:.::......|.:...||||:..|..||:.|||.|..   ..||||.||::|
  Rat   334 RGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGKVTM---DGRVNGGLNLSR 395

  Fly   334 SIGDY----------SLEAVIAEPDFVDVQLNEAHDFLVLGTDGLWDHVPESLIIETVYDSLADT 388
            :|||:          ..:.:.|.||...:.|.:.|:|:|:..||:|:.:....:::.:...::..
  Rat   396 AIGDHFYKRNKNLPPQEQMISALPDIKVLTLTDDHEFMVIACDGIWNVMSSQEVVDFIQSKISQR 460

  Fly   389 TMK-----LDDIPKLLIEAAKERDSQ------DNITAVVVLLKPRHQIE 426
            ...     |..|.:.|::.....|:.      ||:|.:::..|||:.:|
  Rat   461 DENGELRLLSSIVEELLDQCLAPDTSGDGTGCDNMTCIIICFKPRNTVE 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10376	NP_609899.1	PP2Cc	160..419	CDD:238083	76/348 (22%)
Ppm1g	NP_671742.1	PP2Cc	25..>110	CDD:214625	15/77 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	118..139		6/20 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	162..325		28/180 (16%)
		PP2Cc	<321..502	CDD:238083	53/183 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	510..542		111/504 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0631
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810