DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10376 and Ppm1b

DIOPT Version :9

Sequence 1:	NP_609899.1	Gene:	CG10376 / 35126	FlyBaseID:	FBgn0032702	Length:	428	Species:	Drosophila melanogaster
Sequence 2:	NP_001152968.1	Gene:	Ppm1b / 19043	MGIID:	101841	Length:	477	Species:	Mus musculus

Alignment Length:	244	Identity:	72/244 - (29%)
Similarity:	124/244 - (50%)	Gaps:	26/244 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   195 FFGVFDGHSGSLSATYATSQLPQLLA---DQLKANPDPAAFSP--DFYRNAFESAFLLADE---R 251
            ||.|:|||:||..|.|.::.|.:.:.   |...|:...:|..|  :..:....:.||..||   .
Mouse    55 FFAVYDGHAGSRVANYCSTHLLEHITTNEDFRAADKSGSALEPSVESVKTGIRTGFLKIDEYMRN 119

  Fly   252 FTQKK---ITSGTTSVCALITKDQLYIAWVGDSKALLVGKRTQLQLVKPHKPENPDERKRIETAG 313
            |:..:   ..||:|:|..:::...:|....|||:|:|..........:.|||.||.|::||:.||
Mouse   120 FSDLRNGMDRSGSTAVGVMVSPTHMYFINCGDSRAVLCRNGQVCFSTQDHKPCNPVEKERIQNAG 184

  Fly   314 GTVLHAQGQWRVNGILNVARSIGDYSL----------EAVIAEPDFVDVQLNEAHDFLVLGTDGL 368
            |:|:..    ||||.|.|:|::|||..          :.|..||:..::...|..:|:||..||:
Mouse   185 GSVMIQ----RVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEIVRAEEDEFVVLACDGI 245

  Fly   369 WDHVPESLIIETVYDSLADTTMKLDDIPKLLIEAAKERDSQDNITAVVV 417
            ||.:....:.|.|...| :.:..|:::...:::....:.|:||::.|:|
Mouse   246 WDVMSNEELCEFVKSRL-EVSDDLENVCNWVVDTCLHKGSRDNMSVVLV 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10376	NP_609899.1	PP2Cc	160..419	CDD:238083	72/244 (30%)
Ppm1b	NP_001152968.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
		PP2Cc	23..295	CDD:238083	72/244 (30%)
		PP2C_C	289..365	CDD:369544	2/5 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834840
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0631
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R955
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.770