DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10376 and AgaP_AGAP006171

DIOPT Version :9

Sequence 1:	NP_609899.1	Gene:	CG10376 / 35126	FlyBaseID:	FBgn0032702	Length:	428	Species:	Drosophila melanogaster
Sequence 2:	XP_316230.4	Gene:	AgaP_AGAP006171 / 1276838	VectorBaseID:	AGAP006171	Length:	677	Species:	Anopheles gambiae

Alignment Length:	352	Identity:	92/352 - (26%)
Similarity:	146/352 - (41%)	Gaps:	89/352 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   128 KLTDNSEVDRLKDFADEAAPENCECHQQKE----------------PLHTSAAVKNKPRK----- 171
            |.||.:|..:     |..||::......|:                .:.:|::.|..|:.
Mosquito   259 KSTDAAEPGK-----DNCAPDSSSSDGSKQQASKLNGDLGKVGSSGAVSSSSSAKPSPKNGPPPA 318

  Fly   172 --------------MEDRCVCLDRFGEMYELLDKTTRF-FGVFDGHSGSLSATYATSQLPQLLAD 221
                          .:|.....:.|....|..|.|:.. .|..|...||              |:
Mosquito   319 DVSMSMDDTDDDDDDDDESDSDEEFPHAEEPADDTSSTDEGEEDAEEGS--------------AE 369

  Fly   222 QLKANPDPAAFSPDFYRNAFESAFLLADERFTQKKIT------SGTTSVCALITKDQLYIAWVGD 280
            :.:..||..|...: |.|..::||:        |.||      ||.|:|.||:....||:|..||
Mosquito   370 EEEEEPDEYADMGE-YINEEDAAFM--------KTITDEPGKDSGCTAVVALLHGKDLYVANAGD 425

  Fly   281 SKALLVGKRTQLQLVKPHKPENPDERKRIETAGGTVLHAQGQWRVNGILNVARSIGDY------S 339
            |:.::......|::...||||:..|.:|||.|||.|. ..|  ||||.||::|:|||:      |
Mosquito   426 SRCVVCRNGKALEMSFDHKPEDTVEYQRIEKAGGRVT-LDG--RVNGGLNLSRAIGDHGYKMNKS 487

  Fly   340 LEA----VIAEPDFVDVQLNEAHDFLVLGTDGLWDHVPESLIIETVYDSLADTTMKLDDIPKLLI 400
            |.|    :.|.||...:.:....:|:||..||:|:.:....:::.|.:.:....|||..|.:.|.
Mosquito   488 LPAEEQMISALPDIEKITVGPEDEFMVLACDGIWNFMTSEQVVQFVQERINKPGMKLSKICEELF 552

  Fly   401 EAAKERDSQ------DNITAVVVLLKP 421
            :......::      ||:||::|..||
Mosquito   553 DHCLAPHTRGDGTGCDNMTAIIVQFKP 579

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10376	NP_609899.1	PP2Cc	160..419	CDD:238083	82/300 (27%)
AgaP_AGAP006171	XP_316230.4	PP2Cc	14..>107	CDD:214625
AgaP_AGAP006171	XP_316230.4	PP2Cc	<385..577	CDD:238083	65/202 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0631
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810