DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10376 and LOC101734231

DIOPT Version :9

Sequence 1:	NP_609899.1	Gene:	CG10376 / 35126	FlyBaseID:	FBgn0032702	Length:	428	Species:	Drosophila melanogaster
Sequence 2:	XP_004912576.1	Gene:	LOC101734231 / 101734231	-ID:	-	Length:	386	Species:	Xenopus tropicalis

Alignment Length:	312	Identity:	58/312 - (18%)
Similarity:	102/312 - (32%)	Gaps:	118/312 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 LHRSTQQLE-----------QDLCFAKECEVTVEGPPQYDLLKLQKFVASEF------EKYILKL 129
            |..|||:||           .|:.:           |.|.:...|..::.:|      |:.:|:.
Frog    32 LQGSTQRLESSSVLQGIIRPHDMKY-----------PVYMMQMYQNLISGKFKGPSIREEPVLQE 85

  Fly   130 TDN---------SEVDR--LKDFADEAAPENCECHQQKEPLHTSAAVKNKPRKMEDRCVCLDRFG 183
            :|.         ::||.  :..|...:...:.|....:..:|..:               |:||.
Frog    86 SDTVLNLIAKGCTQVDSRWILSFDMSSVSISSELRLAELRIHLPS---------------LERFQ 135

  Fly   184 ----EMYELLDKTTRFF-GV----FDGHSGSLSATYATSQLPQLLADQLKANPDPAAFSPDFYRN 239
                ::|.......:|| |.    |.|.|||   ::....:.|:|...|            :.:.
Frog   136 NVTLDIYHTKGNLEKFFLGSLTIDFPGTSGS---SWKVFNVTQMLQRYL------------YQKE 185

  Fly   240 AFESAFLLADERFTQKKITSGTTSVCALITKDQLYIAWVGDSKALLVGKRTQLQLVKPHKPEN-- 302
            :|.|      :::||.|.||......              |...|| .:|..|.:....||.:
Frog   186 SFSS------DKYTQPKATSQAEQKI--------------DCNGLL-SERIMLMVFSTDKPSSKL 229

  Fly   303 PDERKRIETA--------------GGTVLHAQGQWRVNGILNV---ARSIGD 337
            ......||||              .|...|.:.::.:|.|:..   ::.:||
Frog   230 TGSTSLIETAESSKYVITEADTRETGKRRHRRNRYALNSIIRSSFHSQPVGD 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10376	NP_609899.1	PP2Cc	160..419	CDD:238083	40/206 (19%)
LOC101734231	XP_004912576.1	TGFb_propeptide	50..186	CDD:366248	28/176 (16%)
LOC101734231	XP_004912576.1	TGF_beta_NODAL	284..385	CDD:381637
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165164270
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930