DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10341 and SPBC30D10.15

DIOPT Version :9

Sequence 1:	NP_609898.1	Gene:	CG10341 / 35125	FlyBaseID:	FBgn0032701	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	NP_596270.1	Gene:	SPBC30D10.15 / 2540349	PomBaseID:	SPBC30D10.15	Length:	516	Species:	Schizosaccharomyces pombe

Alignment Length:	585	Identity:	133/585 - (22%)
Similarity:	231/585 - (39%)	Gaps:	123/585 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 EQPAAVKASAPIEEPQSTETAVELGKHSTLKADLSIDKLETATTEATNAVVEPVEMEQQVENELV 68
            :..:.|:.|..:....|:...|   |...:.::||||.:.|...       :|::     :|.|
pombe    17 DDESKVEKSKQLSTNASSSNFV---KEDQIPSNLSIDNINTPQG-------DPID-----KNNL- 65

  Fly    69 NESTQAMTSTTTQEKVVGSVNNLVEEQQCVEMEFETSSDLVVQGSPSEESKKVASDASATVTAPQ 133
            |.:|:.........:.:.|.|:...:|:..|:.|.::.|:.......::..|        :....
pombe    66 NTNTENNLPNIVNFQNISSANSGEIKQKDNEILFSSTEDINQHKENYQDENK--------IDLLD 122

  Fly   134 VQPAPHVDSSPQASGLSLLAAYSSDDSDDEKVTPVQNGDNDVIEVPVTDPASSTTAYRPVVAVSS 198
            |..|...|....:||  ||.......|::|...|..| .::...|.:.|..:..|.....:..||
pombe   123 VALANPKDCVVPSSG--LLMPKEEFISNEEVGIPATN-SSEKSNVKIADEIAEVTHSNSSIGKSS 184

  Fly   199 DDESSKSSSSSSDSDSDSEGEYLTVLRKKIDKRINTVDCDEDDEDFDEDGATGDRSRRRQPPKVR 263
            .|.||.|||.|..:.|.||.:.                    :|:..|:.:..:......|||.
pombe   185 ADLSSDSSSDSESNTSFSETDV--------------------EEEKAEEKSDAESMAPSTPPKT- 228

  Fly   264 GEMLLDDLPP--IHQLEITVPEDECVE-LGKVQSIVDQLVLV--SVLPNSMLFDLDTVLFLEKGR 323
                :::||.  ..:.||.:..:..:| |||:..::.:.|:|  .:....::||..|||..| .|
pombe   229 ----VNELPEQIYEKPEIVLQPNSLIEPLGKIIQVLKREVVVKSDIDDEKIVFDEKTVLCFE-DR 288

  Fly   324 KVLGEVFDVLGQVSDPLYCVRFNSNKQILDRGIKIGDVVYCAPKTEHTQFVILSKLMQVRGSDAS 388
            .::|.:.:..|.||.|.|.|||::.::.......:|..|:..|...:.  :....|..::|||||
pombe   289 SIIGYIHETFGPVSSPYYIVRFSTEEECSAINACMGRPVFYVPTMANK--IDPEPLKYIKGSDAS 351

  Fly   389 WEHDVEPPARYVDHSDDEEEREARAEQRKRRQRDRTNSTDSVDTVTSVATTATKASSVAPPPRQR 453
            ..:|.|......:.||||.|..|:..::||::                     ||.|:.
pombe   352 NVYDEEINPSEQEFSDDEAEVAAKQLKKKRKR---------------------KAKSMV------ 389

  Fly   454 GRRGQRESFRQSQRPSINQHN-QNQPQDEQYNFHPSYNPGSWHSNYYQN------YHQAAANFNM 511
              .|.:....::...|:||:| :|.|   .|..:...||.:  ..:.|.      |..:.::.|.
pombe   390 --SGNQALPGEANFQSLNQNNVRNYP---FYQTNQGSNPPA--KRFTQEPPSSSLYSLSESSINY 447

  Fly   512 AQQHPGMPFPVPNYGYGMPYAMP--PMY-----------PHMYPPPPPFAPPP-----PNNQSHQ 558
            :.|.| |.:   ||.|..|...|  |:|           |.||......||||     ||::.::
pombe   448 STQSP-MYY---NYNYPQPSFPPFHPIYNDSIGYYSQANPQMYYANQVSAPPPQGSFDPNSKFYR 508

Fly 559 558
pombe 509 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10341	NP_609898.1	Gar1	269..403	CDD:282290	37/138 (27%)
SPBC30D10.15	NP_596270.1	Gar1	233..371	CDD:282290	40/140 (29%)
SPBC30D10.15	NP_596270.1	RCR	<449..515	CDD:304939	19/64 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	57	1.000	Domainoid score	I3122
eggNOG	1	0.900	-	-		E1_KOG2236
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	83	1.000	Inparanoid score	I1815
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003330
OrthoInspector	1	1.000	-	-		oto100865
orthoMCL	1	0.900	-	-		OOG6_104062
Panther	1	1.100	-	-	LDO	PTHR31633
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R792
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.940