DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10338 and rusf1

DIOPT Version :9

Sequence 1:	NP_001286056.1	Gene:	CG10338 / 35124	FlyBaseID:	FBgn0032700	Length:	417	Species:	Drosophila melanogaster
Sequence 2:	XP_005164087.1	Gene:	rusf1 / 555936	ZFINID:	ZDB-GENE-070410-89	Length:	435	Species:	Danio rerio

Alignment Length:	386	Identity:	159/386 - (41%)
Similarity:	230/386 - (59%)	Gaps:	23/386 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 VLQKVFLPKGYPDSVSEDYAAYQIWDTAQAFCSTICGTLCTHAILKGIGVGSENINAFSATATWI 112
            |.:.||||:|||:||||||..||:|||.|||.|::.|||.|.|.|:|:|||::.....:||.||:
Zfish    50 VFKSVFLPQGYPESVSEDYLQYQLWDTVQAFSSSLSGTLATQASLRGVGVGNQEATVAAATITWL 114

  Fly   113 LKEGSGHVGRIVFAWWQGSQLDVDSKKWRLRADFLNDLAMGIEIYVLPKYPHFSTQILCCSTLLK 177
            |::|:|.:|||:|||.:||:||.::|||||.||.|||:||.||| ..|.:|.|.|.|:|.:.:.|
Zfish   115 LRDGTGMLGRILFAWLKGSKLDSEAKKWRLFADILNDVAMFIEI-AAPHFPPFFTIIVCIAGIFK 178

  Fly   178 AIVGVAGGATRSALTQHHALRGNLADVASKDSSQETCVNLVASFVGLYLLSLIKSQAVL-YTIFY 241
            :||||||||||:|||.|.|.|.|:||:::||.||||.|||....|.|.|:.|:....:| :.:||
Zfish   179 SIVGVAGGATRAALTVHQARRNNMADISAKDGSQETLVNLAGLLVSLALIPLVTDNPLLTFILFY 243

  Fly   242 VVVSLHLYANLKAVRAVCLRSFNESRYLIALEEFFRSSRMLSPQQVNAMERVTVG--QTVSVSLN 304
            :...|||:||.||||:|.:.:.||:|..|.|.::....::|||.:.|..|.|.:.  :||.:.|.
Zfish   244 LFTVLHLFANYKAVRSVVMETLNEARLSIVLHQYLLHGQVLSPAEANQREPVFLSFRRTVPIKLG 308

  Fly   305 IKLG----------LSVKNLIDEY----KSSSVIENIVSSFDPHEHFIIAQTKKCLGVYLHFETR 355
            ::||          |::||....|    |:.:|...:.|.....:.........|:...||.|:
Zfish   309 VRLGDLIHEPGDLQLALKNNSKPYLIGIKNGAVCVCLGSDASVDDEIKAVCQALCVSAVLHNES- 372

  Fly   356 PQDVLKAYFFAVSYLQDRNQL-KEKYWDIQTKWQEFLALAQQEGWLIHHHLLLVDEYRLDW 415
               .|.|....:|..:|...| .:.:..|...:|.||....:..|.....||..:|:|::|
Zfish   373 ---PLPAVLQQLSNTKDPWALISQSHKMIDEIFQTFLKELDRAKWQTDRTLLDWNEWRVEW 430

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10338	NP_001286056.1	DUF647	40..279	CDD:282708	122/231 (53%)
rusf1	XP_005164087.1	DUF647	43..281	CDD:309836	122/231 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582213
Domainoid	1	1.000	249	1.000	Domainoid score	I2098
eggNOG	1	0.900	-	-		E1_KOG4249
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11232
Inparanoid	1	1.050	272	1.000	Inparanoid score	I2966
OMA	1	1.010	-	-		QHG58480
OrthoDB	1	1.010	-	-		D1357597at2759
OrthoFinder	1	1.000	-	-		FOG0007387
OrthoInspector	1	1.000	-	-		oto39152
orthoMCL	1	0.900	-	-		OOG6_102741
Panther	1	1.100	-	-	LDO	PTHR12770
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4769
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.770