Protein Alignment CG10383 and F17H10.1

DIOPT Version :9

• Sequence 1: NP_001286055.1
• Gene: CG10383 / 35123
• FlyBaseID: FBgn0032699
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_510177.1
• Gene: F17H10.1 / 181439
• WormBaseID: WBGene00008925
• Length: 506
• Species: Caenorhabditis elegans
• Alignment Length: 701
• Identity: 145/701 - (20%)
• Similarity: 256/701 - (36%)
• Gaps: 253/701 - (36%)

  Fly    86 ISVIINPIGKWW-----KAAKHSV--AWRLLNIAQTGSQPERLKAVQQLICMDHLKDWDFRHLAQ 143
            ||.|......:|     |....||  |.:|||:....|  |.|:.:|      |.:..:|  |..
 Worm    11 ISAIYGVYKSYWPDQNDKKIILSVDDAVKLLNVNTNTS--EALRFIQ------HTESKEF--LKS 65

  Fly   144 ICDARTAVSLARCNADTRWFMPVPRRGCIKNPKMLLSE-----------------LHVMLARLRP 191
            :..|..|: |||..::.  .|.:|.:.|: :.|:.::|                 ::.:......
 Worm    66 LNPAAVAL-LARSGSEL--CMKIPIKSCL-DQKLDVTEALRKFNLGDKWNSSIEWINRVACPEED 126

  Fly   192 MACIDHFFSKYFPEQDPIEDIHE-----YLTQEQTIVLSTADTDLLKEIISFLHHITKDPEVSAR 251
            ::|.|.:..: .|.|  ||.:..     |||.|:|..:|..|.|    ::.||.::..:
 Worm   127 LSCSDEWLVR-LPSQ--IERLRRMLQLLYLTTEKTFDVSAIDVD----VVPFLFNVYAE------ 178

  Fly   252 LMRDGGLVHLMELRKIFNDDNETLSTLC-KVLANMSLVPDAVEH---FFTSGWVGALAEWQQCPD 312
                            |...|..::.|. |:|||  :|.:..::   ...|.|:         |.
 Worm   179 ----------------FYHSNVDIAVLAIKILAN--IVGEDEKYAKSMLDSEWL---------PL 216

  Fly   313 LRLQVISAKTMAN--LDH-------DDPNQCTY--PPNVYPLHPRVRTRRKPKADIVFVHGLLGG 366
            :...|.:.|::..  |.|       .......|  ..:||.::   ....:|:.|||.:|||.|.
 Worm   217 ISTMVTNGKSLMERLLSHKVCQNALSSLRSINYRLSSDVYEMY---LPDEEPEIDIVLIHGLRGS 278

  Fly   367 VFITWRQRDRKPTELGLYGKNAFYTSETDDVFLVGEQKRLSGGKLKPGEAVKNVNGNQKTETIKD 431
            |..||||:|                  :|:..|
 Worm   279 VAYTWRQKD------------------SDENLL-------------------------------- 293

  Fly   432 PVLKASKKVEEQRLNISDAATKEFVETLRNEAELDSDWEVVHPDVPLNANEECEGKFSVCGSEWR 496
                                                                             
 Worm   294 ----------------------------------------------------------------- 293

  Fly   497 NQDTSEEYTNCWPMEWLPDDYPDS-RILGIDYTSAVTEWSANFTKYCPCEKGQGHIDVRANTLLD 560
                    ::|||.:|||.|.... ||:|::|.|.:..::..          |..:..|:....:
 Worm   294 --------SSCWPKDWLPLDIKKPFRIIGLEYPSYIFHFTGT----------QQSLQTRSERFKE 340

  Fly   561 RISASDVGNDRPIVWIGHSMGGLLTKLILLKSLDSQEPKVQQLTKNTKGIVFLGTPHRGSPIAKW 625
            ::..:.:|. ||:::|.|||||||.|.:|:.|.:        |.|||.|::|:.|||:|||:|.|
 Worm   341 QLEIAGIGK-RPVLFICHSMGGLLAKKLLIDSTN--------LLKNTVGVLFIATPHKGSPVANW 396

  Fly   626 KQHMQMILSPSIEVKEMEENSPKLLEMHRRFMGCLHTLLRHVKVVSVAEGSPTMLTSFKFPLRIV 690
            .   ..:..|:.:|:.:.||:....:::..|......:...|.:|...|.:  ::.:.|  ..:|
 Worm   397 G---YSVFQPTEDVRMLNENNAINRKLNEDFSAVSKEIPVIVSMVETVESN--IIANAK--SIVV 454

  Fly   691 TEESSKIDFGDFYLLKDDHLSLSKPIYRQSFLYQRLLHVIREAIKERSDPK 741
            ..:|:..:.|..|.:.|.||:|.||. |.|..|..:::.:::.::| ||.:
 Worm   455 PNKSAVFEQGAVYHIADVHLNLCKPT-RDSASYGVIINFLQDCLRE-SDKR 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10383	NP_001286055.1	Abhydrolase	<522..>642	CDD:304388	36/119 (30%)
F17H10.1	NP_510177.1	MhpC	259..>403	CDD:223669	58/291 (20%)
		Abhydrolase	269..>395	CDD:304388	54/267 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1311762at2759
OrthoFinder	1	1.000	-	-		FOG0005732
OrthoInspector	1	1.000	-	-		otm14494
orthoMCL	1	0.900	-	-		OOG6_104869
Panther	1	1.100	-	-	LDO	PTHR48187
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3155
SonicParanoid	1	1.000	-	-		X4128
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.850