Protein Alignment CG10383 and AgaP_AGAP011044

DIOPT Version :9

• Sequence 1: NP_001286055.1
• Gene: CG10383 / 35123
• FlyBaseID: FBgn0032699
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: XP_308092.4
• Gene: AgaP_AGAP011044 / 1269460
• VectorBaseID: AGAP011044
• Length: 767
• Species: Anopheles gambiae
• Alignment Length: 787
• Identity: 337/787 - (42%)
• Similarity: 477/787 - (60%)
• Gaps: 71/787 - (9%)

  Fly    29 GFLLYESPQVRRFLSQYVDKKSPEPDKRRAEYIYIKYHIYRESMRKLKQKEEDEKKWISVIINPI 93
            |.|.||:.:....||..||.:..:.|::|.:|||||:||||:|:|:.....|::.:.:::|:.|.
Mosquito     1 GVLSYEAYRTYAALSSLVDTRVLDIDRKRPDYIYIKHHIYRQSLRERALDAENQHRLLNIIVQPF 65

  Fly    94 GKWWKAAKHSVAWRLLNIAQTGSQPERLKAVQQLICMDHLKDWDFRHLAQICDARTAVSLARCNA 158
            .|||||.|||||||||.|||.|.|.|||||:.||..:||||||||:||||:||.|||:||||.|.
Mosquito    66 EKWWKALKHSVAWRLLRIAQRGDQAERLKAIHQLAQIDHLKDWDFQHLAQLCDYRTAISLARSNC 130

  Fly   159 DTRWFMPVPRRGCIKNPKMLLSELHVMLARLRPMACIDHFFSKYFPEQDPIEDIHEYLTQEQTIV 223
            |||||:|..:.|..|..:.:|.|:..:|..|.|..|..:...:.|....   .|.|....|.|..
Mosquito   131 DTRWFLPPRQYGVEKEMREVLVEMKSLLELLAPHKCAAYALEQTFGSSG---HIREPDGDEVTYQ 192

  Fly   224 LSTA--DTDLLKEIISFLHHIT-----KDPEVSARLMRDGGLVHLMELRKIFNDDNETLSTLCKV 281
            :|.:  :.|.||:.:|.|.|:|     :..:...|::..|||:.|:|..|:|.:|.:....:.::
Mosquito   193 MSPSRFEYDQLKQSLSALVHLTGLVGPEGKQHCRRIVDAGGLLMLLEAEKLFREDIDMKLLISRL 257

  Fly   282 LANMSLVPDAVEHFFTSGWVGALAEWQQCPDLRLQVISAKTMANLDHDDPNQCTYPPNVYPLHPR 346
            :.|:|........|:.|||:|.||.|::..|:|:||.:..|:.|||.||||...|.|.|||||||
Mosquito   258 VGNLSACEGLGYEFYASGWIGILARWKRDVDMRMQVTADLTLENLDQDDPNGFRYAPKVYPLHPR 322

  Fly   347 VRTRRKPKADIVFVHGLLGGVFITWRQRDRKPTELGLYGK-----------NAFYTSETDDVFLV 400
            .|.:.||..|:||:||||||||:||||:|.||....|.||           :..:||.|:|:
Mosquito   323 GRQQAKPAVDVVFIHGLLGGVFVTWRQKDLKPQAASLLGKKHKDVHLVSTSSPSFTSLTNDI--- 384

  Fly   401 GEQKRLSGGKLKPGEA--VKNVNGNQKTETI---KDPVL--KASKKVEEQRLNISDAATKEFVET 458
                       .|.:.  ..|..| |:||.|   ||.:|  :.|.....:..:|||..|||.:|.
Mosquito   385 -----------APTDVDIPPNRTG-QRTEGITAYKDELLTFQESTNSGPRDASISDTETKELIEA 437

  Fly   459 LRNEAELDSDWEVVHPDVPLNANEECE-GK---------FSVCGSEWRNQD-TSEEYTNCWPMEW 512
            |:.|..|.:||.||:|||||.|:|:.. ||         .||.|.:|..:. .|.:.:.||||||
Mosquito   438 LQQEEPLGADWTVVYPDVPLAADEDAHTGKPTATADGATCSVSGDQWLQEPLDSTQRSFCWPMEW 502

  Fly   513 LPDDYPDSRILGIDYTSAVTEWSANFTKYCPCEKGQGHIDVRANTLLDRISASDVGNDRPIVWIG 577
            ||.|:|..|:||:||.|::::|||.   .|||||..|.:..||...|::::.||||.||||:|:|
Mosquito   503 LPKDFPSIRVLGLDYESSLSQWSAT---GCPCEKYDGKLQKRAAEFLEKLATSDVGQDRPIIWVG 564

  Fly   578 HSMGGLLTKLILLKSLDSQEPKVQQLTKNTKGIVFLGTPHRGSPIAKWKQHMQMILSPSIEVKEM 642
            |||||||.|.|::::|:|..|||::|.:|::.::|||||||||.:||.|||...::.||:||:|:
Mosquito   565 HSMGGLLIKSIMVQALESSNPKVRRLAENSRVVMFLGTPHRGSGVAKLKQHTSALVWPSVEVQEL 629

  Fly   643 EENSPKLLEMHRRFMGCLHTL-LRHVKVVSVAEGSPTMLTSFKFPLRIVTEESSKIDFGDFYLLK 706
            ||||..||.:::.|:..:.:| :|..|::::.||.||:|||||..:.:|.|.|::||.|||||..
Mosquito   630 EENSTHLLHLNKSFLRSVDSLGVRRPKIITLCEGKPTVLTSFKLAIHVVPESSARIDAGDFYLTS 694

  Fly   707 DDHLSLSKPIYRQSFLYQRLLHVIREAIKERSDPKDQ---DGQSQSTSNQDVVLVKIVAALLEGA 768
            :|||:|||||.|||||||||:..|:|||:. ..|..|   .|..:|..:         .|.....
Mosquito   695 EDHLNLSKPICRQSFLYQRLVGAIQEAIRS-GGPDSQLIFHGTKKSAGS---------TAASSAL 749

  Fly   769 KGLFESL 775
            .||:..|
Mosquito   750 SGLYTQL 756

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10383	NP_001286055.1	Abhydrolase	<522..>642	CDD:304388	61/119 (51%)
AgaP_AGAP011044	XP_308092.4	Abhydrolase	<558..>629	CDD:304388	39/70 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	611	1.000	Domainoid score	I661
eggNOG	1	0.900	-	-		E1_KOG2029
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41900
Inparanoid	1	1.050	611	1.000	Inparanoid score	I2340
OMA	1	1.010	-	-		QHG47771
OrthoDB	1	1.010	-	-		D1311762at2759
OrthoFinder	1	1.000	-	-		FOG0005732
OrthoInspector	1	1.000	-	-		otm51140
Panther	1	1.100	-	-	LDO	PTHR48187
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4128
TreeFam	1	0.960	-	-
	13	12.940